chapter 24 glossary

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chapter 24 glossary
2014-09-23 11:31:22


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  1. Acetylcholine
    The chief neurotransmitter released into the synapse from the nerve's presynaptic membrane during neurotransmission.
  2. Acetylcholinesterase
    A chemical that breaks down acetylcholine.
  3. Atropine
    A parasympathetic blocker that decreases vagal response.
  4. Benzodiazepines
    Medicines that help relieve nervousness, tension, and other symptoms by slowing the central nervous system.
  5. Defasciculating dose
    A small dose of a non-depolarizing paralytic which, when administered before administering a certain drug, prevents the fasciculations associated with that drug.
  6. Depolarizing neuromuscular blocker
    One of the two major classes of neuromuscular blockers; binds to the acetylcholine receptor and causes the muscle to depolarize or contract.
  7. Ketamine
    A dissociative anesthetic that provides excellent amnesia, analgesia, and anesthesia during procedures and intubation. Most notably, however, it has minimal respiratory depression even at very high doses.
  8. Lidocaine
    A common local anesthetic and antiarrhythmic drug.
  9. Malignant hyperthermia
    A skeletal muscle disease that leads to a life-threatening reaction to succinylcholine and some other inhaled anesthetics.
  10. Medication-facilitated intubation
    The use of adjunctive medications during intubations, either to provide sedation or cause muscular paralysis to protect patients and improve their quality of care.
  11. Narcotics
    A class of drugs known for their ability to induce a profound state of sedation.
  12. Neostigmine
    An acetylcholinesterase inhibitor that can be used to reverse the effects of the competitive (non-depolarizing) NMBAs.
  13. Neuromuscular blocking agents (NMBAs)
    Medications that block transmission of nerve impulses to skeletal muscle at the neuromuscular junction.
  14. Non-depolarizing neuromuscular blockers
    One of the two major classes of neuromuscular blockers; competes with acetylcholine for the receptor but does not cause the receptor to fire.
  15. Sedative
    Medications used to decrease a patient's level of consciousness, lessen irritability, decrease excitability, or cause muscular relaxation.
  16. Succinylcholine
    A depolarizing neuromuscular blocker composed of two acetylcholine molecules hooked back to back.
  17. Vecuronium
    A non-depolarizing neuromuscular blocking agent commonly used by Paramedics in the prehospital setting.