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The flashcards below were created by user
xiongav
on FreezingBlue Flashcards.
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Children: Absorption.
Affected by? (5)
- 1) Age
- 2) disease process
- 3) dosage form
- 4) route
- 5) substances (food, other drugs)
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Children: Distribution.
Affected by? (3)
- 1) More water than fat
- 2) immature liver function.
- 3) immature BBB
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Children: Metabolism.
Affected by? (1)
immature liver
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Children: Excretion.
Affected by? (1)
immature renal system.
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Children.
Why are adverse effects often more severe & more likely to occur?
immature body systems.
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Are med errors more dangerous in children or older adults?
Children. They have IMMATURE body systems.
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Older adults/Geriatrics: Absorption.
Are disease process more likely or age-related changes more likely to alter absorption?
Disease processes
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Older adults/Geriatrics: Distribution.
Affected by? (8)
- 1) Changes in body wt.
- 2) Poor nutrition.
- 3) dehydration
- 4) inactivity
- 5) extended bed rest
- 6) More fat than muscle and decreased body water
- 7) low protein = at risk for adverse effects
- 8) BBB efficiency declines
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Older adults/geriatrics: Metabolism.
Affected by?
Liver's efficiency of metabolism decline w/ age.
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Older adults/geriatrics: Excretion.
Affected by? (1)
Renal efficiency declines.
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What are the main barriers (2) to health care for diversity?
Language and economics.
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Differences in ethnicities and genetics.
Black Americans
Chinese Americans
Mexican Americans
- B: less responsive to beta blockers
- C: different metab. of beta blockers, anti-depressants, & analgesics.
- M: Need lower dose of antidepressants due to variations in metab.
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Why do IM drugs peak faster in men than in women?
Men have more vascular muscles.
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