Therapeutics - Infectious disease 2 - flipped

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kyleannkelsey
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284339
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Therapeutics - Infectious disease 2 - flipped
Updated:
2014-09-29 08:59:25
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Therapeutics Infectious disease
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Therapeutics - Infectious disease
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Therapeutics - Infectious disease
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  1. 90 ug/mL after 1 gram IV
    What are the peak levels for Aztreonam?
  2. Normal renal function: 2 hours
    Renal insufficiency: 6-8 hours
    What is the half-life for Azreonam?
  3. Aztreonam
    What is the only Beta lactam that you can give after a person has had a PCN anaphylactic attack?
  4. 1-2 grams Q6-8H IV
    What is a normal dose for Aztreonam?
  5. Ancef
    What is the brand name for Cefazolin?
  6. Keflex
    What is the brand name for Cephalexin?
  7. Duracef
    What is the brand name for Cefadroxil?
  8. Cefazolin – Ancef (IV)
    Cephalexin – Keflex (oral)
    Cefadroxil – Duracef (oral)(zolexdrox)
    What are the IV 1st generation cephalosporins?
  9. Cephalexin – Keflex (oral)
    Cefadroxil – Duracef (oral)
    What are the oral 1st generation cephalosporins?
  10. Cefazolin – Ancef (IV)
    What are the IV 1st generation cephalosporins?
  11. Renally
    How are 1st generation cephalosporins eliminated?
  12. Surgical prophylaxis 
    MSSA
    E. coli
    P. mirabilis
    UTI
    Strep
    What are the major uses for 1st generation cephalosporins (Cefazolin, Cephalexin, Cefadroxil)
  13. 1-2 grams IV Q8H
    What is the normal dosing for Cefazolin (Ancef)?
  14. 250-1000 mg Q6H PO
    What is the normal dosing for Cephalexin (Keflex)?
  15. 188 ug/mL after 1 gram IV
    What are the peak levels for Cefazolin (Ancef)?
  16. 18 ug/mL after 500 mg IV
    What are the peak levels for Cephalexin (Keflex)?
  17. Normal renal function: 2 hours
    Renal insufficiency: 40-70 hours
    What is the T1/2 for 1st generation cephaolosporins (Cefazolin, Cephalexin, Cephadroxil)?
  18. Monitor for:
    Renal insufficiency
    BMS (if on long term therapy)
    Diarrhea/c. diff (Do a CBC to watch for infection)
    How should you monitor 1st generation cephaolosporins (Cefazolin, Cephalexin, Cephadroxil)?
  19. Delayed hypersensitivity reactions like rashes, etc. (NOT ANAPHYLACTIC)
    When can you use cephaolosporins (Cefazolin, Cephalexin, Cephadroxil) if a person says they have had a PCN allergic reaction?
  20. Cefuroxime (Zinacef, Ceftin)
    Cefaclor (Ceclor)
    Cefprozil (Cefzil)
    Cefotetan (Cefoten)
    Cefoxitin (Mefoxin)
    What are the 2nd generation cephalosporins?
  21. Cefotetan (Cefotan)
    Cefoxitin (Mefoxin)
    Which 2nd generation cephalosporins have particularly good anaerobic coverage and would be used for things like colorectal surgery?
  22. Enterococci
    What type of microbe do no cephalosporinshave activity against?
  23. MSSA
    Group A strep
    S. pneumonia
    Peptostreptococci
    Some community acquired gram negative rods: N. gonorrheae, H. flu, E. coli (a little bit against K. pneumoniae)
    What coverage do 2nd generation cephalosporins (Cefuroxime, Cefaclor, Cefprozil) have?
  24. Similar to Cefuroxime with more B. fragilis activity (though still kind of poor, MIC = 32)
    MSSA
    Group A strep
    S. pneumonia
    Peptostreptococci
    Some community acquired gram negative rods: N. gonorrheae, H. flu, E. coli (a little bit against K. pneumoniae)
    What coverage do 2nd generation cephalosporins (Cefotetan and Cefoxiten) have?
  25. Renal
    2nd generation Cephalosporins are eliminated by what route?
  26. Cefuroxime
    Cefoxitin
    What are the IV 2nd generation cephalosporins?
  27. Cefuroxime
    Cefaclor
    Cefprozil
    What are the Oral 2nd generation cephalosporins?
  28. Anaerobic infections, like colon surgical prophylaxis (Mainly Cefoxiten)
    Otits media or sinusitis (PO versions)
    Streptococcal infections (Though there are better options)
    What are the 2nd generation cephalosporins (Cefuroxime, Cefaclor, Cefprozil, Cefoteten, Cefoxiten) mainly used for?
  29. 2grams IV Q6-8H
    What is the normal dose of Cefoxitin?
  30. 0.75-1.5 grams IV Q6-8H
    250-500 mg Q8H PO
    What is the normal dose of Cefuroxime?
  31. 250-500 mg Q8H PO
    What is the normal dose of Cefaclor?
  32. 250-500 mg Q12H PO
    What is the normal dose of Cefprozil?
  33. Same as first generation:
    Monitor for:
    Renal insufficiency
    BMS (if on long term therapy)
    Diarrhea/c. diff (Do a CBC to watch for infection)
    Cefoxitin: has MTT side chain that interferes with Vit K, so watch PT/PTT
    How should you monitor 2nd generation cephaolosporins (Cefuroxime, Cefaclor, Cefprozil, Cefoteten, Cefoxiten)?

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