In a bovine leukocyte response, the ___________ is depleted, while the __________________ is slow.
marrow reserve; marrow hyperplastic response
In a bovine leukocyte response to acute inflammation,
the first 6-24 hours is indicated by ___________
after the first 24 hours, you will find ...
in 3-4 days you will find...
leukopenia, neutropenia with or without a degenerative left shift;
normal or mild leukocytosis with a neutrophilia and a left shift
In a bovine leukocyte response to chronic inflammation, you may find...
normal or mild neutrophilia
What are the 3 mechanisms of neutropenia?
shift from circulating to marginating pool, increase migration of cells into the tissues, decreased production or release from BM
What are 5 causes of neutropenia?
overwhelming inflammation/infection, increased margination due to an endotoxin (large animals), damage to the BM by viruses, hormones drugs, neoplasia, BM disease, immune mediated in dogs, or idiopathic
The specific growth factor for eosinophils.
Eosinophils are found distributed in...
epithelial surfaces in GI tract, subcutis, lungs, repro tract
Causes of eosinophilia. (5)
(3 W's- worms, wheezes, and weird diseases) hypersensitivity and immune-mediated diseases (allergies, asthma), parasitism, recovery phase of acute infection, Addison's disease, Neoplasms (mast cell tumors)
Causes of eosinopenia. (2)
steroid response, acute inflammation
Causes of basophilia. (3)
heartworm in dogs, allergic reactions, mast cell tumor