More substitution gives the __, which is attained when the __—that is, when [ES]=[E]T
. Thus: Vmax
. More substitution into another equation gives __
At very low substrate concentration, when [S] is much less than __, V0
= __; that is, the reaction is __ with the rate directly proportional to the __. At very high substrate concentration, when [S] is much greater than __, V0
=__; that is, the rate is __. The reaction is __, independent of substrate concentration.