N315 Exam 2

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MeganM
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285470
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N315 Exam 2
Updated:
2014-10-12 20:13:35
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N315
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N315 exam 2
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  1. Impairs iron absorption; & when combined with alcohol or simple carbs can increase uric acid.
    Allopurinol
  2. Aluminum antacids depletes what?
    phosphate and calcium
  3. Decreases absorption of vit A,C,D, magnesium, thiamine, folacin, & iron.
    Aluminum antacids
  4. Large amts of these types of foods can prolong the action of antihistamines.
    • alkaline
    • (milk, cream, almonds, alcohol)
  5. Aspirin can cause ____ deficiency when ____ or more are taken daily.
    • vitamin C
    • 12
    • *also causes thiamine deficiency
    • & can cause iron deficiency (GI bleeding)
  6. Absorption of calcium supplements is decreased by what?
    • foods rich in oxalate (spinach, rhubarb, celery, peanuts)
    • phytic acid (oatmeal, & other grain cereals)
    • phosphorous (chocolate, dried beans, dried fruit, PB)
  7. Lg amts of _______ can delay excretion of Chlorpromazine HCl.  The drug can also increase ______.
    • alkaline foods
    • bld cholesterol
  8. Cimetidine reduces _____ absorption.
    iron
  9. Calcium carbonate antacids cause deficiencies of what?
    • phosphate
    • folacin
    • iron
    • thiamine
  10. Furosemide increases excretion of what?
    • Ca++
    • Mg++
    • K+
    • Zn
  11. Levodopa effectiveness is REDUCED by what?
    high protein diet
  12. Theophylline effectiveness is REDUCED by what?
    high carb diet
  13. What increases the risk of Digitalis toxicity?
    calcium supplements
  14. Aspirin can decrease effects of?
    spironolactone
  15. Aspirin can INCREASE effects of?
    • oral antidiabetics
    • oral anticoagulants
    • cortisone-like drugs
    • penicillins
    • phenytoin
  16. _______ can increase effects of Aspirin.
    large doses of vitamin C
  17. _______ can decrease effects of Aspirin.
    antacids
  18. _______ can decrease the effects of eye drops used for treating glaucoma.
    Meperidine
  19. What's the big deal about Meperidine in older adults?
    Older adults have decreased renal fxn. Meperidine is excreted by kidneys = higher risk of toxicity
  20. Avoid administering other meds within ______ of antacid.
    2 hrs
  21. _____ and _______ can increase INR.
    Mango & Papaya
  22. Avoid ______ with anticonvulsants (carbamazepine, lamotrigine, valproate, gabapentin, phenytoin).
    grapefruit (can cause toxicity)
  23. Verapamil can increase blood _____ level.
    digoxin
  24. Decreased _____ can raise plasma levels of drugs.
    CO
  25. ______ & _______ could cause higher drug levels in plasma & might need a lower dose of med.
    Dehydration & Hypoalbuminemia
  26. Four things that decrease the metabolism of drugs and can cause toxic levels of drugs.
    • dehydration
    • hyperthermia
    • immobility
    • liver disease
  27. Why is the metabolism of drugs affected with older adults?
    • liver size and fxn is decreased
    • hapatic BF decreases by 45% b/w 25-65 yoa
  28. Best absorption routes.
    • inhaled
    • topical
    • IV

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