NON INSULIN INJECTABLES

  1. Pramlintide
    A synthetic pancreatic hormone that mimics the hormone amylin.
  2. how does symlin help a type 1 or 2 diabetic patient?
    it would be good for someone who uses mealtime insulin and fails to achieve glucose control with insulin alone.
  3. T or F: Pramlintide causes hyperglycemia
    FALSE> This medication has a blackbox warning for HYPOGLYCEMIA
  4. Why does pramlintide cause nausea?
    Because it is helping to slow the stomach contents so nausea may be persistent.
  5. Symlin helps decrease a1c? T or F
    True, symlin has been shown to greatly improve POST-PRANDIAL glucose which in turn helps decrease a1c.
  6. What is important when starting pramlintide and insulin dosing?
    recommended to decrease mealtime (bolus) insulin by 50%
  7. T or F: It's okay not to worry about carb counting when starting symlin?
    False, it's very important to consume at least 30 grams of cho in a meal
  8. What are the 3 meds that mimic incretins?
    BYETTA, VICTOZA, and BYDUREON
  9. What is the function of GLP-1 and GIP?
    • *Insulin secretagogues (cheerleaders to produce more insulin)
    • *brain- promotes satiety
    • *alpha cells- decreases glucagon secretion
    • *liver-reduces hepatic glucose output
  10. BYETTA
    EXENATIDe-
  11. Who is the enzyme enemy of GLP-1?
    DPP-4 enzyme
  12. Why is DPP-4 an enemy?
    It destroys GLP-1 (incretin) which encourages insulin production. If GLP is destroyed, then the cheerleader is quiet therefore no longer cheering to produce insulin
  13. When do you use a DPP-4 inhibitor medication?
    Along with BASAL insulin
  14. are dosing adjustments necessary with DPP4-inhibitors?
    No.
  15. what condition would you NOT use DPP-4 inhibitors
    gastroparesis or pancreatitis, or kidney problems
  16. what diabetic med helps w/ weight control?
    GLP-1
Author
janeg70
ID
285832
Card Set
NON INSULIN INJECTABLES
Description
meds
Updated