NON INSULIN INJECTABLES
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A synthetic pancreatic hormone that mimics the hormone amylin.
how does symlin help a type 1 or 2 diabetic patient?
it would be good for someone who uses mealtime insulin and fails to achieve glucose control with insulin alone.
T or F: Pramlintide causes hyperglycemia
FALSE> This medication has a blackbox warning for HYPOGLYCEMIA
Why does pramlintide cause nausea?
Because it is helping to slow the stomach contents so nausea may be persistent.
Symlin helps decrease a1c? T or F
True, symlin has been shown to greatly improve POST-PRANDIAL glucose which in turn helps decrease a1c.
What is important when starting pramlintide and insulin dosing?
recommended to decrease mealtime (bolus) insulin by 50%
T or F: It's okay not to worry about carb counting when starting symlin?
False, it's very important to consume at least 30 grams of cho in a meal
What are the 3 meds that mimic incretins?
BYETTA, VICTOZA, and BYDUREON
What is the function of GLP-1 and GIP?
- *Insulin secretagogues (cheerleaders to produce more insulin)
- *brain- promotes satiety
- *alpha cells- decreases glucagon secretion
- *liver-reduces hepatic glucose output
Who is the enzyme enemy of GLP-1?
Why is DPP-4 an enemy?
It destroys GLP-1 (incretin) which encourages insulin production. If GLP is destroyed, then the cheerleader is quiet therefore no longer cheering to produce insulin
When do you use a DPP-4 inhibitor medication?
Along with BASAL insulin
are dosing adjustments necessary with DPP4-inhibitors?
what condition would you NOT use DPP-4 inhibitors
gastroparesis or pancreatitis, or kidney problems
what diabetic med helps w/ weight control?
What would you like to do?
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