Therapeutics - UTI 2

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kyleannkelsey
ID:
285841
Filename:
Therapeutics - UTI 2
Updated:
2014-10-14 18:54:44
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Therapeutics UTI
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Therapeutics - UTI
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Therapeutics - UTI
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  1. How old should a patient be to take Cipro or Levo for UTI?
    >16 years
  2. What is the dose of Nitrofurantoin macrocrystals for a short course treatment of UTI?
    100 mg PO BID x 5 days
  3. What CrCl is required of a patient receiving Nitrofurantoin macrocrystals for UTI?
    >50 (some say 60)
  4. What are the indications for a 7-14 day UTI therapy?
    • Men > 40 years
    • Pre-existing renal disease
    • Pregnancy
    • Re-infection or resistant infection
    • Children not indicated for 3 day therapy
  5. What are the DOC for a 7-14 UTI antibiotic therapy?
    • TMP/SMX
    • Amoxicillin/clavulanate or Amoxacillin
    • Nitrofurantoin microcrystals
  6. TMP/SMX would be a poor choice for what group of patients when treating UTI?
    • Pregnancy 1st trimester (teratogen)
    • Pregnancy last trimester (causes hyperbillirubinea in the infant)
  7. What is the dose indicated for a 7-14 day treatment with Amoxacillin/clavulanate for UTI?
    875 mg PO BID
  8. What is the dose indicated for a 7-14 day treatment with Amoxacillin for UTI?
    500 mg PO TID
  9. What group of patients should not receive Nirofurantoin macrocrystals for UTI?
    • Pregnancy last trimester (causes hyperbillirubinea in the infant)
    • CrCl <50 (or some say 60)
  10. What is the dose of Nitrofurantoin macrocrystals for a 7-14 day treatment of UTIs?
    100 mg PO BID
  11. What are the supportive therapies for UTI?
    • Fluids
    • Urinary analgesics
    • Antipyretics
  12. What is the urinary analgesic usually used for UTI?
    Phenazopyridine
  13. When should you treat asymptomatic bacteruria?
    When pregnant or a child
  14. What is the minimum treatment length for pyelonephritis?
    10-14 days
  15. What antibiotics are used for outpatient treatment of Pyelonephritis?
    • TMP/SMX
    • Cipro
  16. What is the dose of Cipro for the treatment of pyelonephritis?
    250-500 mg PO BID
  17. What are the indications for inpatient treatment of pyelonephritis?
    • Unable to tolerate oral meds
    • Dehydration/Hypotension
    • Pediatric/elderly
    • Immunocomprimised
    • Pregnant
  18. What drugs are given for inpatient therapy for pyelonephritis?
    • Cipro
    • Ceftriaxone
    • Piperacillin/tazobactam
    • Aztreonam
    • Aminoglycosides (gentamicin or tobramycin)
    • Ampicillin
  19. What is the dose of ciprofloxacin for the inpatient treatment of pyelonephritis?
    200-400 mg IV Q12H x 10-14 days
  20. What is the dose of ceftriaxone for the inpatient treatment of pyelonephritis?
    1 gram IV Q24H x 10-14 days
  21. What is the dose of piperacillin/tazobactam for the inpatient treatment of Pyelonephritis?
    3.375 gm IV Q12H x 10-14 days
  22. What group is piperacillin/tazobactam particularly good for when treating inpatients for pyelonephritis?
    Nursing home or hospital acquired patients, which have a higher pseudomonas risk
  23. How long should you treat a patient with pyelonephritis for?
    10-14 days
  24. What is the dose for gentamicin or tobramycin for the treatment of pyelonephritis?
    • 3-5 mg/kg/day divided in multiple daily doses
    • Or
    • 7mg/kg/24 hours QD
  25. What is the dose for Ampicillin for inpatient treatment of pyelonephritis?
    12 grams IV Q6H
  26. When should you stitch an inpatient from IV to PO when treating pyelonephritis?
    • Absence of fever for 24 hours
    • Able to tolerate PO medications
  27. How are recurrent pyelonephritis infections treated?
    • Usually by adding 7 days onto the treatment
    • Should be cultured to make sure the drug is adequate
  28. When should a patient receive prophylactic therapy for pyelonephritis?
    > or = to 3 infections per year
  29. How do you treat a patient with > or = to 3 pyelonephritis infections per year and is related to intercourse?
    • TMP/SMX 1 tab
    • Nitrofurantoin 50-100 mg
    • Cephalexin 250 mg
    • Empty bladder and take after intercourse
  30. How do you treat a patient with > or = to 3 pyelonephritis infections per year that is not related to intercourse?
    • TMP/SMX 0.5 tabs HS or 3x/week
    • Nitrofurantoin 50-100 mg HS
    • Norfloxacin 200 mg HS
    • Cephalexin 250 mg HS
  31. What should you counsel a patient on when they are receiving medications for UTI?
    • Expected outcome
    • Antibiotic information
    • Importance of compliance
    • How to prevent future occurrence

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