Therapeutics - Bacterial Prostatitis/UTIs

Card Set Information

Author:
kyleannkelsey
ID:
286956
Filename:
Therapeutics - Bacterial Prostatitis/UTIs
Updated:
2014-10-24 13:31:37
Tags:
Therapeutics Bacterial Prostatitis UTIs
Folders:
Therapeutics - Bacterial Prostatitis/UTIs
Description:
Therapeutics - Bacterial Prostatitis/UTIs
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user kyleannkelsey on FreezingBlue Flashcards. What would you like to do?


  1. What are the pathogens of bacterial prostatitis?
    • E.coli
    • Pseudomonas spp.
    • Proteus mirabilis
    • Klebsiella pneumoniae
    • Neisseria gonorrhea
  2. How long is the treatment course for bacterial prostatitis?
    prolonged antibiotic course (4-12 weeks)
  3. What are the DOC for bacterial prostatitis?
    Quinalones or tmp/smx are drugs of choice
  4. Are quinalones recommended for treatment of N gonorrhea bacterial prostatitis?
    No
  5. What are the advantages of Bactrim for UTIs?
    • effective
    • available in variety of dosage forms
    • twice daily dosing
    • relatively well tolerated
    • inexpensive
  6. What are the disadvantages of Bactrim for UTIs?
    • allergic reactions which may be life threatening
    • IV dosing is confusing
    • should be avoided during last trimester of pregnancy
    • dosage adjustment with renal impairment
  7. What are the advantages of Quinalones for UTIs?
    • excellent gram negative activity
    • available both oral and IV
    • oral bioavailability ~ IV
    • once-twice daily dosing
    • superior prostatic tissue penetration
  8. What are the disadvantages of Quinalones for UTIs?
    • expensive
    • CI in children and pregnancy
    • many significant drug interactions
    • adjust dosage with renal impairement
  9. What interactions are common with Quinalones?
    • Warfarin - prolonged bleeding time
    • Theophylline - elevated serum theophylline levels
    • Caffeine - insomnia, jitteriness
    • Calcium, aluminum and iron - dramatic decrease in absorption if taken at the same time
  10. What are the advantages of ampicillin and amoxicillin in the treatment of UTIs?
    • well tolerated
    • effective against Enterococci
    • inexpensive
    • safe for use during all phases of pregnancy and pediatrics
  11. What are the disadvantages of ampicillin and amoxicillin in the treatment of UTIs?
    • developing resistance
    • 10% of population is allergic
    • TID dosing frequency
  12. What are the advantages of aminoglycosides in the treatment of UTIs?
    • excellent efficacy against all gram negative organisms
    • generally well tolerated
    • inexpensive?
  13. What are the disadvantages of aminoglycosides in the treatment of UTIs?
    • renal and ototoxicity
    • difficult dosing
    • serum concentration monitoring required
    • not available orally
  14. What are the advantages of cephalosporins in the treatment of UTIs?
    • good to excellent coverage against MOST gram negative pathogens
    • easily dosed
    • very well tolerated
    • available oral and parenteral
  15. What are the disadvantages of cephalosporins in the treatment of UTIs?
    • not reliable with short course therapy
    • no activity against enterococcus
    • no oral agent effect against Pseudomonas aer.
    • Expensive

What would you like to do?

Home > Flashcards > Print Preview