Clin Path- WBC Parasites.txt

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Author:
Mawad
ID:
287245
Filename:
Clin Path- WBC Parasites.txt
Updated:
2014-10-27 17:57:50
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WBC parasites
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vet med
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  1. Ehrlichia canis
    Cells infected-
    Vector-
    Lab Findings-
    Therapy-
    • Cells infected- monocytes
    • Vector- brown dog tick
    • Lab Findings- Thrombocytopenia (acute and subclinical), pancytopenia w/ non-regenerative anemia (chronic)
    • Therapy- Tetracycline/doxycycline
  2. German shepherds are predisposed to ____________ infection because of defective cellular immunity.
    Ehrlichia canis
  3. What are the clinical syndromes associated with Ehrlichia canis infection?
    acute, subclinical, and chronic
  4. What is the hallmark of chronic Ehrlichia canis infection?
    pancytopenia (nonregenerative anemia, neutropenia, and thrombocytopenia)
  5. In acute Ehrlicia canis infection, the organism replicates in host ________, resulting in _______.
    macrophages; vasculitis
  6. In acute Ehrlichia canis infection, thrombocytopenia is due to... (3)
    immune-mediated destruction, vasculitis, and splenic sequestration
  7. In chronic Ehrlichia canis infection, decreased production of hematopoietic cells is due to... (3)
    immune-mediated destruction, ste cell depletion, and altered BM microenvironment
  8. Ehrlichia ewingii
    Disease-
    Cells infected-
    Vector-
    Lab Findings-
    Therapy-
    • Disease- canine granulocytic ehrlichiosis
    • Cells infected-granulocytes
    • Vector- lone star tick
    • Lab Findings- thrombocytopenia, nonregenerative anemia, inclusions in granulocytes, eosinopenia, lymphopenia, neutrophilia
    • Therapy-tetracycline
  9. Ehrlichia chaffeensis
    Disease-
    Cells infected-
    Vector-
    Lab Findings-
    • Disease- Humon monoccytic ehrlichiois (dogs are reservoir)
    • Cells infected- mononuclear cells
    • Vector- ticks (Amblyomma americanum)
    • Lab Findings- thrombocytopenia, lymphocytosis
  10. Feline ehrlichiosis
    Cells infected-
    Vector-
    Lab Findings-
    Therapy-
    • Cells infected- monocytes
    • Vector- ticks
    • Lab Findings- thrombocytopenia, nonregenerative anemia, morulae in monocytes
    • Therapy- Doxycycline
  11. Transmission of the 3 anaplasma phagocytophilum (all 3 strains) is by _________.
    Ixodes ticks (ften co-infected with Lyme disease agent)
  12. Anaplasma phagocytophilum (in Equines)
    Cells infected-
    Vector-
    Lab Findings-
    Therapy-
    • Cells infected-neutrophils and eosinophils
    • Vector- Ixodes ticks
    • Lab Findings- thrombocytopenia, leukopenia
    • Therapy- Oxytetracycline
  13. When diagnosing equine granulocytic ehrilichiosis, first rule out...
    EIA with Coggins test (very similar symptoms)
  14. The pathogenesis of equine granulocytic ehrlichiosis involves ________.
    vasculitis
  15. Anaplasma phagocytophilum (in Canines)
    Cells infected-
    Vector-
    Lab Findings-
    Therapy-
    • Cells infected- neutrophils and eosinophils
    • Vector- Ixodes tick
    • Lab Findings- thrombocytopenia, nonregenerative anemia, lymphopenia
    • Therapy- tetracycline
  16. Anaplasma phagocytophilum (in felines)
    Cells infected-
    Vector-
    Lab Findings-
    Therapy-
    • Cells infected- neutrophils and eosinophils
    • Vector- Ixodes tick
    • Lab Findings- thrombocytopenia, hyperglobulinemia
    • Therapy- tetracycline
  17. Anaplasma phagocytophilum (in bovines)
    Cells infected-
    Vector-
    Lab Findings-
    • Cells infected- neutrophils, eosinophils, and monocytes
    • Vector- Ixodes tick
    • Lab Findings- thrombocytopenia, neutropenia
  18. Neorickettsia risticii
    Disease-
    Cells infected-
    Vector-
    Lab Findings-
    Therapy-
    • Disease- Equine monocytic ehrlichiosis
    • Cells infected- monocytes and macrophages
    • Vector- trematode (caddis flies and mayflies)
    • Lab Findings- thrombocytopenia, leukopenia (maybe with rebound leukocytosis)
    • Therapy- oxytetracycline
  19. What are the clinical sign of equine monocytic ehrlichiosis?
    diarrhea, colic, laminitis
  20. Neorickettsia helminthoeca
    Disease-
    Cells infected-
    Vector-
    Lab Findings-
    Therapy-
    • Disease- Salmon poisoning in dogs
    • Cells infected- monocytes
    • Vector- trematodes (ingestion of infected salmon)
    • Lab Findings- lymphopenia, throbocytopenia
    • Therapy- tetracyclines
  21. Leishmania infantum (L. donovani-less common)
    Disease-
    Cells infected-
    Vector-
    Lab Findings-
    • Disease- Leishmaniasis in dogs
    • Cells infected- macrophages
    • Vector- female sandflies (take blood meal for reproduction)
    • Lab Findings- thrombocytopenia, hypergammaglobulinemia, immune-mediated hemolysis, azotemia
  22. There is an increased risk in _________ for infection with Leishmania infantum.
    foxhounds
  23. With Leishmania infantum infection, there is ___________ and ____________ clinical signs, and circulating immune complexes may cause... (3)
    lymphadenopathy and hepatosplenomegaly; vasculitis, arthritis, and glomerulonephritis (acute inflammation of the kidney, typically caused by an immune response)
  24. Clinical signs of infection with Leishmania infantum include.... (3)
    cutaneous lesions, epistaxis, diarrhea
  25. Hepatozoon americanum
    Disease-
    Cells infected-
    Vector-
    Lab Findings-
    Therapy-
    • Disease- canine hepatozoonosis
    • Cells infected- neutrophils and monocytes
    • Vector- ticks
    • Lab Findings- marked neutrophilic leukocytosis, nonregenerative anemia
    • Therapy- anticoccidial drugs

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