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How do skeletal muscles contract?
- 1. action potential is initiated by the firing of a motor neuron
- 2. depolarization of the motor nerve ending releases ACh
- 3. ACh diffuses across synaptic cleft and binds to membrane receptors
- 4. membrane channels open and allow Na+ to enter the muscle cell
- 5. entry of Na+ shifts membrane potential in a positive direction and polarization occurs
What triggers a skeletal muscle contraction?
generation of an action potential on the sarcolemma
What's different about smooth muscle contractions?
- brought about by variable stimuli
- contraction is much slower
What's different about cardiac muscle contractions?
- don't require nerve stimulation but still need an AP
- AP slower than in skeletal muscles
- contraction time and AP are the same
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