ch4 mental health drugs

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  1. antidepressant meds
    MAOI's
    monoamine oxidase inhibitor blocks enzyme that metabolizes norepinephrine and serotonin

    special diet-avoid tyramine-in aged food and beverages..cheese wine... and avoid cough medicine w pseudoephedrine to prevent hypertensive crisis

    phenelzine(Nardil) and tranylcypromine (parnate)
  2. TCAs Tricyclic Antidepressants
    • Block norepinephrine & serotonin receptors thereby increasing norepinephrine at the synapse.-dizziness & hypotension/risk for falls-cardiotoxicity
    • Elavil (amitripytylline)
    • anafranil (clomipramine)
    • norpramin (desipramine)
    • toframil (imipramine)
    • pamelor(nortriptylline)
    • asendin (amoxapine)
  3. SSRI (selective serotonin reuptake inhibitors)
    • Prevent reuptake of serotonin
    • -suicidal impulses, anxiety, insomnia, sex dysfx,
    • GI problems
    • -slow tapering to avoid withdrawal
    • Escitalopram (Lexapro)
    • Fluvoxamine (Luvox)
    • Paroxetine (Paxil)
    • Sertraline (Zoloft)
    • Fluoxetine (Prozac) or (Sarafem) for PMS
    • Citalopram (Celexa)
  4. SNRIs
    serotonin-norepinephrine reuptake inhibitors
    • increase levels of serotonin and norepinephrine
    • also used for neuropathic pain
    • Duloxetine (Cymbalta)
    • Desvenlafaxine (Pristiq)
    • Venlafaxine (Effexor)
  5. SNDIs
    serotonin -norepinephrine disinhibitors
    Remeron (antianxiety/antidepressant)
  6. NDRIs
    Norepinephrine-dopamine reuptake inhibitors
    • Bupropian (Wellbutrin)
    • Trazadone (Desyrel)
  7. Lithium (Eskalith, Carbolith, Lithane)
    • Mood Stabilizer for Bipolar
    • -works at cellular level Na/K to stabilize electrical activity & decrease mania
    • -cardiac dysrhythmias, seizures
    • -check kidney functioning and thyroid levels
    • toxic > 1.5 meq/L drawn 8 hrs after 
    • Therapeutic  0.4 - 1.3
  8. Mood Stabilizers-Antimanic Drugs
    often in conjunct with Lithium
    • Anticonvulsants: enhance GABA, decrease mania
    • Divalproex sodium (Depakote)
    • Carbamazepine (Tegretol)
    • Oxcarbazine (Trileptal)
    • Lamofrigine (Lamictal)
    • Gabapentin (Neurontin)
    • Topiramate (Topamax)

    • Valproic Acid (Depakene)
    • Oxcarbezepine (Trileptal)
  9. First Generation/conventional(typical) Antipsychotics
    • Bind to dopamine receptors and reduce transmission
    • decrease positive schizophrenia symptoms
    • cost effective
    • -EPS, Tardive dyskinesia, NMS
    • "phenothiazines"
    • Chlorpromazine (thorazine)-low potency
    • -orthostatic hypotension
    • Haloperidol (Haldol) -high potency
    • -less sedating, fewer anticholinergic effects
    • -More EPS
    • Fluphenazine (Prolixin)
    • Pherphenazine (Trilafon)
    • Thioridazine (Mellaril)
  10. anticholinergic effects
    dry mouth, blurred vision, constipation, urinary hesitancy, tachycardia
  11. Adverse effects of receptor blockage of antipsychotic agents
    Image Upload
  12. Second Generation/Atypical antipsychotics
    • Colzapine (Clozaril): *agranulocytosis *
    • Olanzapine (Zyprexa) : weight gain
    • Risperidone (Risperdal) : EPS, orthostatic  hypotension, sedation
    • Quetiapine (Seroquel) : Sedation, orthostatic hypotension, weight gain
    • Ziprasidone (Geodon) : dizziness, sedation & dysrhythmias
    • aripiprazole (Abilify) : headache, insomnia, nausea
    • Paliperidone (Invega)
    • -fewer EPS/NMS
    • -Affect negative & positive symptoms of schizophrenia
    • -improves cognition

Card Set Information

Author:
murleyman
ID:
287332
Filename:
ch4 mental health drugs
Updated:
2014-10-31 16:54:28
Tags:
mental health drugs
Folders:
nursing
Description:
nursing drugs
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