LAT Computer version

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katyhershley
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287820
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LAT Computer version
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2014-11-10 07:03:54
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Laboratory Animal Technician
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Study for LAT exam
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  1. Which of the following describes that a facility must do to comply with the AWA?
    1. Animal Welfare Assurance
    2. PHS Policy
    3. AWR
    4. Ag Guide
    3. Animal Welfare Regulations
  2. Who can restrict or withdraw approval of the Animal Welfare Assurance if an institution fails at it's responsibilities?
    1. OLAW
    2. IACUC
    3. USDA
    4. FDA
    1. OLAW Office of Laboratory Animal Welfare
  3. What document is published by the institute of Laboratory Animal Research and gives guidance on creating/implementing an occupational health/safety program?
    1. The Guide
    2. Bio safety in Microbiological and Biomedical Labs
    3. Occupational Health and Safety in the Care and Use of Research Animals
    3. Occupational Health and Safety in the Care and Use of Research Animals.
  4. The first step in reporting noncompliance is to:
    1. Inform the USDA of the noncompliance
    2. confront the individual(s) who are not complying
    3. Notify the news of the noncompliance
    4. Consult your institutional policy for how to report noncompliance
    4. Consult your institutional policy for mechanisms for reporting non-compliance.
  5. Which of the following is the least potent sterilizer?
    1. Gamma Radiation
    2. Beta Radiation
    3. UV radiation
    3. They are all the same
    3. UV radiation
  6. Which method of monitoring the effectiveness of sanitation or sterilization uses spores in a vial?
    1. Microbial Swabs
    2. Biological Indicators
    3. RODAC plates
    4. Bio luminescence monitoring
    2. Biological indicators
  7. Saphenous Vein (lower leg) is used to collect blood from which animals?
    Usually small animals
  8. Where are IP injections given? *what quadrant?*
    Lower right quadrant
  9. Subchronic tests last how long?
    3 months, or 10% of lifespan
  10. Chronic studies last for how long?
    6 months to a year with multiple exposures: lifespan of animal.
  11. Total blood volume in an animal's body equals approx ? of it's total body weight?
    6%
  12. LD50 is what?
    Lethal dose to kill 50% of test population
  13. Where are quadriceps located?
    Anterior (towards the front) of femur (upper rear limb bone)
  14. If a blood tube lid is red it is used for?
    Serum, no anticoagulant
  15. If a blood tube lid is green it is used for?
    Plasma, chemistry tests
  16. If a blood tube lid is purple it is used for?
    Plasma, hematology
  17. Segment 1 test?
    Toxicology in reproduction animals
  18. What is a teratogen?
    Substance that damages a developing fetus
  19. Subacute studies last low long?
    1 month
  20. Acute toxicology involves exposure for how long?
    Short periods, less than 24 hours
  21. What percent of blood/body weight can be safely taken every two weeks?
    1% of body weight
  22. What animal has anterior vena cava bleeding site?
    Birds, fish, turtles
  23. Formula for Area?
    L x W
  24. Lateral tail vein in mice use what gauge needle?
    26-28
  25. Which animals get injections to anterior vena cava?
    Pig, Guinea Pig
  26. For solutions: 1% = ?mg/ml
    10mg/ml
  27. Segment 3 study?
    Toxicity in newborn pups, gestation, parturition and lactation
  28. Route of administration PO
    by mouth, orally
  29. Segment 2 study?
    Toxicity study in fetuses
  30. 1lb = ?kg
    .454 kg
  31. What process is a standard way to chlorinate water?

    1. Add sodium thiosulfate
    2. Use municipal water from the tap
    3. Let water sit for 12 hours
    4. Expose the water to sunlight
    1. add sodium thiosulfate
  32. What membrane attaches the tendons to the long bone?
    1. Diaphysis
    2. Epiphysis
    3. Medullary Cavity
    4. Periosteum
    4. Periosteum
  33. What is the formula for the area of a room or cage?
    Area=length x width
  34. What is the role of hemoglobin molecules?
    1. transport nutrients
    2. scavenge for foreign material
    3. transport respiratory gases
    4. maintain shape of red blood cells
    3. to transport respiratory gases
  35. How many chambers does a mammal heart have?
    4
  36. What is the true stomach called in a ruminant?
    1. Rumen
    2. Reticulum
    3. Omassum
    4. Abomasum
    4. Abomasum
  37. What is the sac of connective tissue surrounding the heart called?
    1. Myocardium
    2. Pericardium
    3. Epicardium
    4. Endocardium
    2. Pericardium
  38. Which lymph nodes are found in the armpit?
    1. Mesenteric
    2. Axillary
    3. Inguinal
    4. Popilteal
    2. Axillary
  39. What is lymph derived of?
    1. Secretions of the parotid glands
    2. Excreted fluid from kidneys
    3. Fluids from the gastrointestinal tract
    4. Extracellular fluid of body tissues
    D. Extracellular fluid of body tissues
  40. How many litters before a mouse is retired?
    6-7
  41. How does pleural fluid aid respiration?
    1. it assists in exchange of gasses
    2. it washes out debris from lungs
    3. it lubricates the chest wall and lungs to prevent friction
    4. it maintains proper pH in the lungs
    3. It lubricates the chest wall and lungs to prevent friction
  42. What acts like an insulator and makes the nerve appear white?
    1. Glands
    2. Synapses
    3. Axons
    4. Myelin
    4. Myelin
  43. What motion occurs when a bone is moved away from the body from the midline?
    1. rotation
    2. flexion
    3. abduction
    4. adduction
    3. abduction
  44. Which muscle group has voluntary movement?
    1. Skeletal
    2. Cardiac
    3. Smooth
    4. All of the above
    1. Skeletal
  45. What is occurring when the lymph nodes become swollen and painful?
    1. the lymph was damaged
    2. bacteria,virus,tumor cells multiplying in node
    3. lymph is blocked
    4. lymph is performing a function
    2. bacteria,virus,tumor cells multiplying in node
  46. Which lymph nodes are found in the rear leg?
    1. Mesenteric
    2. Axillary
    3. Inguinal
    4. Popliteal
    4. Popliteal
  47. Which lymph nodes are found in the groin?
    1. Mesenteric
    2. Axillary
    3. Inguinal
    4. Popliteal
    3. Inguinal
  48. How do cells absorb nutrients?
    Nutrients in the blood diffuse out of the capillaries into the extracellular fluid that surrounds the cell
  49. Urine flows from the kidney to the urinary bladder through what structure?
    1. Urethra
    2. Nephron
    3. Medulla
    4. Ureter
    4. ureter
  50. What is a transgenic mouse?
    1. has DNA from a different source
    2. has had DNA removed or disabled
    3. differs from another strain by one gene
    4. has genetic makeup of 2 strains
    1. has DNA from a different source
  51. What does it mean if an animal is considered a wild type?
    1. a new gene has been inserted
    2. a gene has been turned off
    3. does not contain gene of interest
    4. has homozygous alleles of interest.
    3. does not contain genes of interest
  52. what is the relaxation phase of heart called?
    1. Diastole
    2. Systole
    3. Mitral
    4. Aortic
    1. Diastole
  53. Which animals lack a gallbladder?
    Horses and rats
  54. The liver produces what to aid in digestion?
    Bile, which is stored in the gallbladder
  55. What does the pancreas produce?
    Digestive enzymes, insulin and glucagon
  56. What are ureters?
    Transport urine from kidneys to bladder
  57. What is urethra?
    Transports urine from bladder to outside of body
  58. What is the main function of the kidney?
    Filters blood, forming urine with water and wastes from the blood (kidneys made up of nephrons)
  59. Thyroxine is produced by what gland?
    Thyroid
  60. All genes in an organism are collectively referred to as?
    Genome
  61. Different versions of the same genes are called?
    (individuals of same species have same genes, but different versions)
    Alleles
  62. When a gene is turned off or absent due to a mutation, the gene is referred to as?
    • Null
    • (both copies of the gene are absent or turned off)
  63. Animals that have had DNA from a different source inserted into their genome are referred to as?
    Transgenic
  64. When a small electrical current is passed through a solution containing genes and stem cells, which causes DNA to enter the cells it is called what?
    Electroportation
  65. An animal with some of its cells containing new gene and some without the new gene is called a?
    Chimera
  66. Which animal is known to form a monogamous pair when breeding?
    Gerbils
  67. What breeding scheme has one male paired with multiple females and are kept together?
    Harem
  68. What breeding scheme has one male paired with multiple females who are removed when determined pregnant?
    Polygamous
  69. Whitten Effect is what?
    When a male is put with a group of females to initiate estrus
  70. How many generations of sister to brother matings to be considered inbred?
    At least 20
  71. An animal with a mutation that differs from other animals of that strain, usually by just a single mutant gene is called?
    Congenic
  72. What is the target age for weaning rodents?
    21 days
  73. How old is a mouse when shes retired from breeding?
    9 months or after 6-7 litters
  74. Gestation of a cat?
    60 days
  75. Gestation of a rabbit?
    30 days
  76. Gestation of a dog?
    60 days
  77. Gestation of NHP?
    6 months
  78. Gestation of swine?
    3 months
  79. Which animals are induced ovulators?
    Rabbits, Cats and Ferrets
  80. Another name for average?
    Mean
  81. 5% solution refers to what?
    5 parts solute per 100 parts of the solution

    so 50mg/ml
  82. 2.2% solutions refers to what?
    2.2 parts solute per 100 parts of the solution

    so 22mg/ml
  83. what gauge of needle to use on mouse, rat, cat, dog?
    23-25
  84. Nude mice usually lack what gland?
    Thymus gland, they lack T cells
  85. A substance that causes a fever is called a ?
    Pyrogen
  86. SCID mice lack which cells?
    T and B
  87. Asplenic mice lack what?
    Spleen
  88. Beige mice lack what?
    NK cells (Natural Killer cells)
  89. What directly stimulate immune cells to produce antibodies and prolong absorption of an antigen from the injection site?
    Adjuvant
  90. Freund's incomplete adjuvant does not contain what?
    Mycobacteria cells, therefore don't cause any undesirable side effects
  91. in vitro means?
    In cell
  92. in vivo means?
    In an animal
  93. When a cancer cell fuses with a hybrid cell it's called a?
    hybridoma
  94. Inside the abdominal cavitiy, the hybridoma cells grow and fluids accumulate. The antibodies in this fluid is called?
    ascites
  95. Suture material is rated 1 - 6, which is the thickest?
    6
  96. Material, Absorbability and Filament type are all characteristics of what?
    Suture materiel.
  97. When sterilizing in heated beads, how long do the instrument tips stay in there?
    Sterilized in approx 10 seconds, not to stay in longer than 1 minute.
  98. Liquid chemical sterilization, "cold" sterilization uses what chemicals?
    paracetic acid, hydrogen peroxide
  99. Asepsis means?
    free of pathogenic microorganisms
  100. What is the typical surgical antiseptic?
    povidone iodine or chlorohexidine
  101. How many times do you apply a surgical antiseptic before survival surgery?
    3 times
  102. Common gas anesthetics are?
    Isoflurane and sevoflurane
  103. Capillary refill time of a healthy animal is?
    2 seconds or less
  104. to check for good perfusion you do what?
    look for pink color on the foot
  105. What is recumbency?
    animal lies down for long periods and refuses to get up
  106. Etiology refers to?
    cause or origin of the disease
  107. Diseases an animal is born with is called a ? disease
    congenital
  108. Prions are what?
    protein particles
  109. Disease transmission occurs from one generation to the next is referred to as?
    vertical transmission
  110. Disease transmission occurs within the same generation is referred to as?
    horizontal transmission
  111. What are living organisms called that trasmit disease? Like fleas and ticks?
    Vectors
  112. What are contaminated non-living objects that can cause disease transmission called?
    Fomites
  113. A sudden disease outbreak that affects a large number of animals is called?
    Epizootic
  114. A disease commonly occurring in multiple members of a population is called?
    enzootic
  115. TPR stands for?
    body temperature, pulse rate, respiration rate
  116. Loss of voluntary muscle coordination is called?
    Ataxia
  117. How does The Guide describe a Policy?
    A practical statement of collective wisdom
  118. According to the Guide, who is not required on the IACUC?
    1. Veterinarian
    2. Committee Chair
    3. Scientist
    4. Public Member
    2. Committee Chair
  119. The IACUC should meet how often?
    As often as necessary to fill obligations
  120. If an animal has undergone major survival surgery and the investigator requests another, which agency must approve that?
    USDA must approve multiple survival surgeries.
  121. Who is responsible for providing formal on the job training to personnel caring for animals?
    The institution
  122. When is it permissible to use non-pharmaceutical grade substances on animals?
    When permission is granted from IACUC
  123. What is recommended air changes per hour?
    10-15
  124. Storing animal feed at less than ?C is recommended?
    21 degrees C
  125. Most dry lab animal diets can safely be used how many months after the manufacturing date?
    6 months
  126. Providing nude mice with cotton bedding material can lead to what?
    Conjunctivitis
  127. Cedar bedding is not recommended why?
    Because it can emit aromatic hydrocarbons
  128. How often should solid bottomed rodent cages be sanitized?
    Once per week
  129. How often should primary enclosures and cage accessories be sanitized?
    Every two weeks
  130. When inbred animals are used it is important to monitor their genetic what?
    Authenticity
  131. The environmental enrichment program should be reviewed regularly by which group?
    The IACUC, researchers and vet staff
  132. Facility design, CFD stands for?
    Computational Fluid Dynamics
  133. unrelieved pain may lean to a phenomenon called?
    "Wind Up"
  134. How can cost analysis be used?
    To reveal which services are most cost effective.
  135. What species may have blood drawn from the venous plexus?
    Rat
  136. What size needle would be used for an ID injection in a rabbit?
    27 gauge
  137. What nerve is close to the muscles posterior to the femur?
    Sciatic nerve
  138. What species has a palatal ostium?
    Guinea Pig
  139. What is the maximum amount of blood that should be taken from a 3.5 kg rabbit every 2 weeks?
    35 ml
  140. What are recombinant inbred strains used for?
    determining gene linkage
  141. What color is a mouse with the genotype B/b
    Black
  142. What is coitus?
    Insemination of a female by a male
  143. How are targeted mutation mice used?
    Effects of a missing gene are studied
  144. What is the term for genes that affect the same trait?
    Allelic genes
  145. What is the term used for an animal with cells from 2 different lineages?
    Chimera
  146. What is the stage of estrus in which ova develop in the ovary
    Proestrus
  147. What is a fertilized egg called?
    Zygote
  148. What is the term used when more than one dominant allele affects a trait?
    Incomplete dominance
  149. What is the name of the lypmph nodes surrounding the bowel?
    1. Mesenteric
    2. Axillary
    3. Ingunial
    4. Popliteal
    1. Mesenteric
  150. What is the membrane where tendons attach to long bone?
    1. diaphysis
    2. epiphysis
    3. medullary cavity
    4. periosteum
    1. Periosteum
  151. Which is the main shaft of long bone?
    1. diaphysis
    2. epiphysis
    3. medullary cavity
    4. periosteum
    1. diaphysis
  152. Which is the artery that carries unoxyenated blood?
    1. coronary artery
    2. vena cava
    3. pulmonary artery
    4. aorta
    3. pulmonary artery
  153. Where is the roughage broken down in a rabbit?
    Cecum
  154. What is the outer layer of skin called?
    Epidermis
  155. Which of the following is the area where growth occurs in the long bone?
    1. diaphysis
    2. epiphysis
    3. medullary cavity
    4. periosteum
    2. epiphysis
  156. What is the valve between the right atrium and right ventricle?
    1. Aortic valve
    2. mitral valve
    3. tricuspid valve
    4. pulmonary valve
    3. Tricuspid valve
  157. What is another name for the pituitary gland?
    1. Hypophysis
    2. Thyroid
    3. Adrenal
    4. Parathyroid
    1. hypophysis
  158. What is ganglia?
    Cluster of nerves
  159. What does the left atrium do?
    1. pushes blood to the lungs
    2. collects blood from the body
    3. collects blood entering the heart from the lungs
    4. pushes blood to the body
    3. collects blood entering the heart from the lungs
  160. What percentage of blood is plasma in animals?
    55%
  161. What is the valve between the left atrium and the left ventricle of the heart?
    1. aortal
    2. mitral
    3. coronary
    4. carotid
    2. mitral
  162. What heart chamber has the thickest wall?
    Left ventricle
  163. Which organization uses the Guide as one of its standards for the accreditation of laboratory animal programs?
    A.IACUC
    B.NSF
    C.AAALAC
    D.PHS
    C. AAALAC
    (this multiple choice question has been scrambled)
  164. What is a quality assurance unit responsible for ensuring compliance with?
    A.Animal Welfare Regulations (AWR)
    B.Public Health Service (PHS) Policy
    C.The Guide
    D.GLPs Regulations
    D. GLP regulations
    (this multiple choice question has been scrambled)
  165. Who can restrict or withdraw approval of the Animal Welfare Assurance if an institution fails at its responsibilities?
    A.FDA
    B.USDA
    C.OLAW
    D.IACUC
    C. OLAW
    (this multiple choice question has been scrambled)
  166. What is the germicidal spectrum of ultraviolet light for killing microorganisms?
    A.50-90 nanometers
    B.100-180 nanometers
    C.200-280 nanometers
    D.300-350 nanometers
    C. 200-280 nanometers
    (this multiple choice question has been scrambled)
  167. What will happen to an aquatic species if the water in the system has too many ions?
    A.Temperature will increase in the tank.
    B.Water will flow into the animal.
    C.Water will flow from the animals’ bodies into the water.
    D.Fatal toxins will accumulate in the tank.
    B. Water will flow into the animal
    (this multiple choice question has been scrambled)
  168. What does pH measure in the aquatic system?
    A.Magnesium ions
    B.Total ions
    C.Calcium ions
    D.Hydrogen ions
    D. hydrogen ions
    (this multiple choice question has been scrambled)
  169. How much dissolved oxygen is normally contained in water (by volume)?
    A.5-8%
    B.10-15%
    C.More than 25%
    D.Less than 1%
    D. less than 1%
    (this multiple choice question has been scrambled)
  170. What is the function of the endocrine system?
    a.Produce hormones
    b.Regulatebody functions
    c.Regulatemetabolic functions
    d.All of the above
    d. all of the above
  171. What do the hormones produced in the adrenal gland regulate?
    a.Protein and carbohydrate metabolism
    b.Electrolyte balance and stress adaptation
    c.Fight or flight responses
    d.All of the above
    d. all of the above
  172. Which technique collects the embryonic stem cells that line the inside of a developing blastocyst to produce embryonic stem cell lines?
    A.Genotyping
    B.Pronuclear injection
    C.Homologous recombination
    d.None of the above
    C. homologous recombination
    (this multiple choice question has been scrambled)
  173. What is it called when a new gene is incorporated in to the germ cells(egg and sperm)?
    A.Genotyping
    B.Germline transmission
    C.Pronuclear injection
    D.Polymerase chain reaction
    B. germline transmission
    (this multiple choice question has been scrambled)
  174. What is the term used to describe a situation where new genes are inserted by a targeted mutation?
    A.Wild type
    B.Hemizygous
    C.Rederived
    D.Knockin
    D. knockin
    (this multiple choice question has been scrambled)
  175. Where are catheters placed?
    a.Blood vessels
    b.Bladder
    c.Spine
    d.All of the above
    d.All of the above
  176. What is the name of a device used to cannulate a blood vessel?
    A.Luer lock
    B.Vascular access port
    C.Tether
    D.Osmotic pump
    B.Vascular access port
    (this multiple choice question has been scrambled)
  177. How does arterial catheterization differ from venous catheterization?
    a.It is used more often as a means to directly measure blood pressure.
    b.Arteries are more difficult to puncture than veins.
    c.It is a more painful procedure.
    d.All of the above
    d.All of the above
  178. What can be implanted for long-term, continuous infusion of a solution to unrestrained laboratory animals?
    A.Vascular port
    B.Sodium gradient pump
    C.Diffusion port
    D.Osmotic pump
    D.Osmotic pump
    (this multiple choice question has been scrambled)
  179. What does hemolysis mean?
    A.Preventing clotting of blood
    B.Reducing the number of clots
    C.Breaking down blood cells
    D.Isolatingplatelets
    C.Breaking down blood cells
    (this multiple choice question has been scrambled)
  180. What does the Limulus amebocyte lysate test assess?
    A.Teratogens
    B.Immunodeficiency
    C.Bacterial pyrogens
    D.Carcinogens
    A.Teratogens
    (this multiple choice question has been scrambled)
  181. What does a B cell defect result in?
    A.Lack of spleen
    B.Hairlessness
    C.Wasting disease
    D.Lack of an antibody response
    D.Lack of an antibody response
    (this multiple choice question has been scrambled)
  182. Which gland can be surgically removed to cause a deficiency in T cells?
    A.Parathyroid
    B.Thymus
    C.Thyroid
    D.Pituitary
    B.Thymus
    (this multiple choice question has been scrambled)
  183. How does irradiation attack the immune system?
    A.It suppresses cell division.
    B.It kills B cells and T cells.
    C.It destroys the thyroid.
    D.It inhibits hemoglobin formation.
    D.It inhibits hemoglobin formation.
    (this multiple choice question has been scrambled)
  184. What is an adjuvant?
    A.A substance that enhances the immune response
    B.A commercially available antigen
    C.A substance to relieve pain when inducing an antibody response
    D.A second antigen to make polyclonal antibodies
    A.A substance that enhances the immune response
    (this multiple choice question has been scrambled)
  185. What is the difference between a monoclonal antibody and a polyclonal antibody?
    A.The polyclonal antibody is made from T-cells.
    B.The polyclonal antibody has a longer life span.
    C.The monoclonal antibody reacts to only one antigen.
    D.The monoclonal antibody reacts with only one site on an antigen.
    D.The monoclonal antibody reacts with only one site on an antigen.
    (this multiple choice question has been scrambled)
  186. For which nutrient study would the rat NOT be an appropriate model?
    A.Protein
    B.Vitamin C
    C.Calcium
    D.Carbohydrates
    B.Vitamin C
    (this multiple choice question has been scrambled)
  187. What is a metabolism cage used for?
    a.Measure food and water intake
    b.Measure feces and urine output
    c.Measure oxygen and carbon dioxide
    d.All of the above
    d.All of the above
  188. How are curved needles classified?
    A.By the degree of tapering of the cutting tip
    B.By the orientation of the triangular apex
    C.By the portion of a circle that their length represents
    D.By the shape of the shaft of the needle
    C.By the portion of a circle that their length represents
    (this multiple choice question has been scrambled)
  189. What is a negative result of using multifilament suture material?
    A.It is harder to tie knots.
    B.It is expensive
    C.It increases the chance for wound infection.
    D.It takes a long time to absorb.
    C.It increases the chance for wound infection.
    (this multiple choice question has been scrambled)
  190. What do the bronchi branch out to?
    bronchioles
  191. Where is CSF found?
    The brain
  192. What vessel becomes blocked causing heart attacks?
    Coronary arteries
  193. What do neutrophils do?
    destroy bacteria/dead cells
  194. What cells contain hemoglobin?
    Erythrocytes
  195. What chemical is commonly used to sterilize surgical instruments?
    1. peracetic acid
    2. formaldehyde
    3. ethylene oxide
    4. glutaraldehyde
    3. Ethylene Oxide
  196. Which of the following is a zoonotic disease?
    1. Herpes B
    2. Arthritis
    3. MHV
    4. Cancer
    1. Herpes B
  197. Special care must be taken with which of the following species during gastric intubation?
    1. guinea pig
    2. rat
    3. rabbit
    4. mouse
    1. Guinea pig (and Chinchilla)
  198. Blood cells that ingest foreign materials and debris are called:
    1. erythrocytes
    2. pathogenic cells
    3. macrophages
    4. viremic cells
    3. macrophages
  199. The word "cannula" can be used in the place of:
    1. tubule
    2. mastitis
    3. catheter
    4. blood vessel
    3. catheter
  200. The Limulus Amebocyte Lysate (LAL) test is an alternative to
    1. using neonatal animals
    2. using tetrogens in fetal development
    3. using monoclonal antibodies
    4. using rabbits in pyrogen testing
    4. Using rabbits (and horseshoe crabs) in testing
  201. The point at which blood pressure is the highest is:
    1. in the vessels in the legs
    2. in the aorta
    3. in the vena cava
    4. in the lungs.
    2. in the aorta
  202. What is the temporary loss of feeling or sensation induced by one or more drugs?
    Anesthesia
  203. What system controls voluntary activity?
    1. autonomic
    2. peripheral nervous
    3. axonal
    4. central nervous
    2. peripheral nervous system (PNS)
  204. Why is it important not to rush when scrubbing down fingers, hands, and arms?
    A.To ensure that no excess water is spilled
    B.To ensure that nothing is dropped during the process
    C.To ensure that the contact time of the scrub on the skin is long enough
    D.To ensure water drains from elbows to fingers
    C.To ensure that the contact time of the scrub on the skin is long enough
    (this multiple choice question has been scrambled)
  205. What type of tumor does not spread?
    A.Stationary
    B.Malignant
    C.Benign
    D.Fixed
    C.Benign
    (this multiple choice question has been scrambled)
  206. What is the route of infection?
    A.How a microorganism enters the body of a host
    B.The way a host responds to the presence of a pathogen
    C.The manner in which a microorganism spreads from one individual to another
    D.How a disease progresses over time
    A.How a microorganism enters the body of a host
    (this multiple choice question has been scrambled)
  207. What is an animal called that spreads an infectious disease while showing no signs of disease?
    A.Responder
    B.Carrier
    C.Sentinel
    D.Transmitter
    B.Carrier
    (this multiple choice question has been scrambled)
  208. What is active immunity?
    A.The immune response to an attack by a foreign substance
    B.The autoimmune response to a chronic infection
    C.The inflammatory response
    D.The transfer of immunity from one animal to anothe
    A.The immune response to an attack by a foreign substance
    (this multiple choice question has been scrambled)
  209. How many vaccines are routinely used for rodents?
    A.1
    B.2
    C.3
    D.0
    D.0
    (this multiple choice question has been scrambled)
  210. What is the treatment schedule when administering insecticide?
    A.Multiple treatments several days apart
    B.One treatment every two weeks
    C.Multiple treatments over one day
    D.One treatment is enough
    A.Multiple treatments several days apart
    (this multiple choice question has been scrambled)
  211. The Animal Welfare Regulations require that protocols for United States Department of Agriculture(USDA)-covered species may only be approved for how long?
    A.1 year
    B.3 years
    C.6 months
    D.2 years
    A.1 year
    (this multiple choice question has been scrambled)
  212. Which organization uses the Guide for the Care and Use of Laboratory Animals(the Guide) as one ofits standards for the accreditation of laboratory animal programs?
    A. (AAALAC)
    B. (PHS)
    C.(IACUC)
    D. (NSF)
    A. (AAALAC)
    (this multiple choice question has been scrambled)
  213. Why can per diem rates differ between institutions?
    A.Some institutions include costs that others do not include.
    B.Some institutions set higher standards for animal care which can add to the cost.
    C.Pharmaceutical companies cannot be compared to university research facilities.
    d.All of the above
    A.Some institutions include costs that others do not include.
    (this multiple choice question has been scrambled)
  214. Intravenous catheters can be left in place for up to how many hours?
    72
  215. Heparin is used for what?
    Prevent clots/obstructions in catheter. (it's an anticoagulant)
  216. What is a common complication in catheterization of the female urethra?
    1. females do not have a urethra
    2. danger of cytocentesis
    3. location of the urethral orifice
    4. small diameter of the urethra
    3. location of the urethral orifice
  217. What is phagocytosis associated with?
    1. electrolytes
    2. leukocytes
    3. etiology
    4. erythrocytes
    2. leukocytes
  218. The minimum moist heat autoclaving time and temperature should be:
    1. 15 minutes at 132 F
    2. 15 minutes at 121 F
    3. 15 minutes at 121 C
    4. 5 minutes at 121 C
    2. 15 minutes at 121 F
  219. Bones are attached to each other at the joints by?
    Ligaments
  220. Muscles are attached to the bones by?
    tendons
  221. What is the term for suture material permanently attached to a needle?
    1. aught
    2. snook-hook
    3. extracting
    4. swaged-on
    4. swaged-on
  222. ____ breeding is a selective system in which parents are of different inbred strains, used to transfer desired mutations from strains.
    Hybrid
  223. What is intensive breeding?
    Where the male always remains with the female
  224. What is nonintensive breeding?
    Where males are housed separately while females are rearing young.
  225. Are inbred strains usually written with a / or : ?
    /
  226. The AWA/AWR:

    requires how many members?
    species it covers?
    Inspections every?
    Enforced by?
    -IACUC - 3 members (chairperson, vet, community member)

    -Species - warm blooded excluding mice/rats    and birds used for research

    -Every 6 months

    -Enforced by USDA
  227. The PHS Policy:

    requires how many members?
    species it covers?
    Inspections every?
    Enforced by?
    - IACUC - 5 members (chairperson, vet, scientist, non-scientist, community member)

    -All vertabrates

    -Inspections for cause

    -Enforced by OLAW
  228. AAALAC performs site visits every?
    3 years
  229. BMBL standards are set by?

    (Biosafety in Microbiological and Biomedical Laboratories)
    set by the CDC and NIH
  230. Who mandates GLP's?
    FDA and EPA
  231. The Guide requires IACUC inspections every?
    6 months
  232. When developing a new drug, what is the order of testing? (3 parts)
    • 1. In Vitro
    • 2. Pre Clinical (with animals) (in vivo)
    • 3. Clinical (with humans)
  233. Animals obtained from shelters must be held for ___ days before being sold to a research facility.
    5 days
  234. APHIS is a part of _____ and administers the ____ and ____.
    Part of the USDA and administers the AWA and AWR
  235. What is the 28 hour law?
    Animals can not be transported for more than 28 hours without being unloaded for 5 consecutive hours for rest, food and water.
  236. What % of an animal facility is devoted to support functions? (total floorspace for lunch rooms, restrooms, meeting rooms, etc.)
    25%
  237. A ____ corridor floor plan is most common and has no separation of traffic by clean or dirty status.
    Single corridor
  238. A ____ corridor floor plan separates clean and dirty traffic in designated halls to reduce contamination. Traffic flow is one way and each room has an entrance and exit door. (dirty hall on one side, clean on the other)
    Two corridor
  239. A ____ corridor floor plan where rooms share a clean hallway and each room has it's own dirty exit, the dirty hall wraps around the outside of the facility.
    Three corridor
  240. Temp ranges in a facility should range between ___ and ___?
    70-76F
  241. What is the smallest size particle a HEPA filter can remove?
    .03
  242. What portion of college and university funds are provided by the federal government?
    2/3
  243. Optimal Neutral pH should be between?
    6.8-7
  244. What ions are usually measured for water hardness?
    Calcium and Magnesium
  245. Flow rate of water in an aquatic tank should be between ___ to ____ exchanges per hour
    5-6
  246. Space inside long bones with red or yellow marrow - where blood cells are produced?
    1. Diaphysis
    2. Epiphysis
    3. Medullary Cavity
    4. Periosteum
    3. Medullary Cavity
  247. What are the 2 types of connective tissue?
    Bone and cartilage
  248. What is the layer of tissue and fat that bind the skin to the underlying tissue - where sub q fluids are given?
    hypodermis
  249. The skin that covers an animal is also called the?
    integument
  250. The vertebrate body consists of how many major organ systems?
    11
  251. What connective tissue includes bone, cartilage, blood and adipose tissue?
    Special

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