Opioids - Pharmacology

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Author:
Pandora320
ID:
290360
Filename:
Opioids - Pharmacology
Updated:
2014-12-01 15:54:46
Tags:
Pharmacology
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Description:
Pharmacology PAP-570
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  1. Which drug is also known as 3-O-methyl-morphine
    Codeine
  2. Which drug has a metabolite that is a non-opioid and has stimulant properties?
    Meperidine – this is why the pupils dilate
  3. Drug that doesn’t have opioid activity
    Dextromethorphan
  4. Will accumulate with repeated administration
    Meperidine
  5. Will cause pupils to DILATE
    Meperidine
  6. Abused in hospital settings
    Meperidine
  7. Why might death occur with an opioid O/D? (What is the physiological process behind it?)
    Respiratory depression
  8. Should not be used in patients with Ischemia or infarction
    Pentazocine
  9. Which drug would you give after GI surgery?
    Meperidine- less GI issues
  10. Which drug can PAs NOT prescribe?
    Buprenorphine (Suboxone)
  11. Which drug can be used to treat alcoholism?
    Naltrexone
  12. Used as maintenance treatment for opioid addiction
    Methadone
  13. Seizures can occur in patients with renal failure
    Meperidine
  14. How do you reverse the respiratory effects of partial agonists/ ag-antagonists
    Nalaxone/opioid antagonist
  15. How are the smooth muscle effects of partial agonists/ag-antag drugs compared to opioid agonists?
    Not as severe
  16. Which drug would you give during labor and delivery?
    Meperidine-less effects on the uterus
  17. Removed from market
    Propoxyphene
  18. What is the gold standard opioid of choice?
    Morphine
  19. Which drug is the main mu partial agonist
    Buprenorphine
  20. Given the pharmacokintetic history of a drug, what matters most when it comes to the withdrawal symptoms of a drug?
    the dose/amount of the last time you took the drug
  21. Which drug is primarily used for cough and is the active ingredient in virtually all OTC cough medicine?
    Demomethotrophn
  22. Used for migraines
    Meperidine
  23. Which one is the preferred opioid of abuse and why?
    Heroin. Lipophilic- gets to brain fast
  24. Which opioid causes histamine release? And how does this manifest itself?
    Morphine- itchy
  25. Methadone vs naltrexone vs buprenorphine
    Opioid Analgesics
  26. Are maintenance tx drugs long acting or short acting
    Long

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