lipid d/o

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Author:
kjp19
ID:
290771
Filename:
lipid d/o
Updated:
2014-12-06 12:32:05
Tags:
lipid meds
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Description:
lipid d/o
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  1. lovastatin
    starting dose __
    maximal dose __
    • 20 mg/day
    • 80 mg/day
  2. pravastatin
    starting dose __
    maximal dose__
    • 40 mg at bedtime
    • 80 mg at bedtime
  3. simvastatin
    starting dose __
    maximal dose __
    • 20 mg at bedtime
    • 80 mg at bedtime
  4. fluvastatin
    starting dose __
    maximal dose __
    • 20 mg at bedtime
    • 80 mg at bedtime
  5. atrovastatin
    starting dose __
    maximal dose __
    • 10 mg at bedtime
    • 80 mg at bedtime
  6. rosuvastatin
    starting dose __
    maximal dose __
    • 10 mg at bedtime
    • 40 mg at bedtime
  7. cholesterol absorption inhibitors
    name of drug __
    dose (only one) __
    used for ____
    • ezetimibe
    • 10 mg per day
    • high ldls
  8. bile acid sequestrants
    drugs 3X __
    • cholestyramine
    • colestipol
    • colesevelam
  9. cholestyramine 
    starting dose __
    maximal dose __
    • 4 gm per day
    • 32 grams per day
  10. colestipol
    starting dose __
    maximal dose __
    • 5 grams per day
    • 40 grams per day
  11. colesevelam
    starting dose __
    maximal dose __
    • 3750 mg day
    • 43375 mg per day
  12. nicotinic acid
    extended release 
    starting dose 
    maximal dose
    • 500 mg at bedtime
    • 2 g at bedtime
  13. fibric acid derivatives

    are used for ?
    elevated triglycerides elevaded remnants
  14. fibric acid derivatives
    gemfibrozil 
    starting dose __
    maximal dose __
    • 600 mg BID
    • 600 mg BID
  15. fibric acid derivatives
    fenofibrate
    starting dose __
    maximal dose __
    • 145 mg daily
    • 145 mg daily
  16. statins mech of action
    decrease cholesterol synthesis, increase hepatic hepatic ldl receptors, decrease vldl production
  17. cholesterol absorption inhibitors
    ezetimibe
    mech of action
    decrease intestinal cholesterol absorption
  18. bile acid sequestrants
    cholestyramine
    colestipol
    colesevelam
    mech of action
    increase bile acid exxreation and increase ldl receptors
  19. nicotinic acid
    mech of action
    decrease vldl hepatic synthesis
  20. fibric acid derivatives
    gemfibrozil
    fenofibrate
    mech of action
    increase lpl, decrease vldlsynthesis
  21. lipid disorders
    visit one (next visit 6 weeks)
    tx __
    • lifestyle changes
    • reduce sat fat and cholesterol intake
    • encourage moderate physical activity
    • referral to a dietitian
    • stop smoking
  22. LDL goals
    0-1 risk factors __
    2+ risk factors __
    CAD and CAD risk factors __
    • <160
    • <130
    • <100
  23. Triglyceride levels
    optimal
    borderline
    high
    very high
    • <150
    • 150-199
    • 200-499
    • >500
  24. LDL levels
    optimal
    near optimal
    borderline high
    high
    very high
    • <100
    • 100-129
    • 130- 159
    • 160-189
    • >190
  25. total cholesterol
    desirable
    borderline high
    high
    • <200
    • 200-239
    • >240

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