Assignment 5 biochem

  1. Which enzymes in the citric acid cycle catalyze oxidative decarboxylation reactions?
    isocitrate dehydrogenase and the alpha-ketoglutarate dehydrogenase complex
  2. The following structures of cyt c in different organisms indicate
    a and b, cyt c undergoes little change during evolution and cyt c is highly conserved
  3. Alpha-ketoglutarate dehydrogenase is most similar to which of the following?
    pyruvate dehydrogenase
  4. Which of the following glycolytic enzymes is not use in gluconeogenesis?
    hexokinase
  5. The regulatory enzymes in gluconeogenesis are
    glucose-6-phosphate, fructose-1,6-bisphosphate, pyruvate carboxylas, and phosphoenolpyruvate carboxykinase
  6. The one enzyme that use iron-sulfer cluster for function in the TCA cycle is
    aconitase
  7. The one reaction of the TCA cycle that is an example of substrate level phosphorylation is catalyzed by
    succinyl CoA synthetase
  8. The major anapleurotic reaction that refills the TCA cycle with oxaloacetate is catalyzed by
    pyruvate carboxylase
  9. The accepting of electrons by which of the following directly contributes to the recycle of NAD+?
    FMN
  10. In the second half of the mitochondrial Q cycle, QH2 donates one electron to cytochrome c, the second electron is passed to.
    CoQ.- (the semi-reduced version of CoQ)
  11. The one reaction of the TCA cycle that produces GTP is catalyzed by
    succinyl CoA synthetase
  12. The coupling of electron transport and ATP synthesis is mediated by
    the proton gradient across the inner mitochondrial membrane
  13. Which of the following enzyme complex is not a proton pump.
    Succinate-Q reductase
  14. Which of the following enzyme complex has the lowest average standard reduction potential?
    NADH-Q oxidoreductase
  15. Which of the following component is the converge point of electrons from NADH and FADH2
    CoQ
  16. Which of the following reaction is catalyzed by Q-cytochrome cOxidoreductase
    QH2+ 2 Cyt c ox+ 2H+matrix→ Q + 2 Cyt c red+ 4H+cytoplasm
  17. The mechanism Cyt C oxidase used to create proton gradient is/are
    • a) pump proton out of the inner membrane
    • c) use matrix proton to make H2O
  18. Which of the following reaction is catalyzed by Catalase?
    2O2·-+ 2H+↔O2+ H2O2
  19. The Q cycle
    Facilitate the transfer of 2 electrons from QH2to the single electron carrier
  20. Which enzymes in the citric acid cycle catalyze reactionsthat produce NADH?
    isocitrate dehydrogenase, alpha-ketoglutarate dehydrogenase, and malate dehydrogenase
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Assignment 5 biochem
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Assignment 5 biochem
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