Home > Preview
The flashcards below were created by user
on FreezingBlue Flashcards.
level of structure of protein that is a sequence of a chain of amino acids
primary protein structure
a level of structure of protein that occurs when the sequence of amino acids are linked by hydrogen bonds
secondary protein structure
a level of structure of protein that occurs when certain attractions are preserved between alpha helices and pleated sheets
tertiary protein structure
a level of structure of proteins that occurs when there are more than one amino acid chains attached together
quaternary protein structure
what are the 3 sources of protein biopharmaceuticals?
- microorganisms (ecoli, yeast, fungal)
- animal cell culture systems
- transgenic animals/plants
what are the 3 parts of upstream processing for biopharmaceutical production?
- 1. get cells from cell bank
- 2. propagation of working bank cells, generating starter cultures
- 3. production scale cell culture
what are the 6 parts of downstream processing for biopharmaceutical production?
- 1. harvest cells to recover crude product
- 2. concentration
- 3. main purification
- 4. final product formulation
- 5. product filling, freezing, drying, and sealing
- 6. labeling and packaging
region of the antigen recognized by an antibody
antibodies secreted from a single B cell, have identical paratopes
any substance capable of eliciting an adaptive immune response
immunoglobulin secreted by B cells
what is the mechanism of action of antibody?
- 1. blocikg /neutralizing action of molecular targets
- 2. antibody-dependent celuular cytotoxicity (mark target cells or immune cell to attack)
- 3. signal molecules
- 4. delivery agents
what is a hybridomas technology?
inject mice with antigen and then fuse immune cells with tumor cells to produce hybridomas. The hybridomas are mass produced and then monoclonal antibodies are isolated.
What would you like to do?
Home > Flashcards > Print Preview