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when heterozygotes have a phenotype in between the two parental alleles
when two alleles affect a phenotype in distinguishable ways
when more than two alleles affect a phenotype
when a gene affects more than one phenotypic character
where a gene at one locus alters the phenotypic expression of a gene at a second locus
when multiple genes are responsible for a phenotype
genetically identical individuals can show different phenotypes as a result of environmental factors
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