Pharmacology - Immune Medications.txt

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bamaguh1988
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Pharmacology - Immune Medications.txt
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2015-01-08 17:22:36
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  1. The client with acquired immunodeficiency syndrome and Pneumocystis jiroveci infection has been receiving pentamidine (Pentam 300). The client develops a temperature of 101° F. The nurse continues to assess the client, knowing that this sign most likely indicates which condition?
    1. That the dose of the medication is too low
    2. That the client is experiencing toxic effects of the medication
    3. That the client has developed inadequacy of thermoregulation
    4. That the client has developed another infection caused by leukopenic effects of the medication
    4. That the client has developed another infection caused by leukopenic effects of the medication
  2. The nurse caring for a client who is taking an aminoglycoside should monitor the client for which adverse effects of the medication? Select all that apply.
    1. Seizures
    2. Ototoxicity
    3. Renal toxicity
    4. Dysrhythmias
    5. Hepatotoxicity
    • 2. Ototoxicity
    • 3. Renal toxicity
    • 4. Dysrhythmias
  3. Ketoconazole is prescribed for a client with a diagnosis of candidiasis. Which interventions should the nurse include when administering this medication? Select all that apply.
    1. Restrict fluid intake.
    2. Monitor liver function studies.
    3. Instruct the client to avoid alcohol.
    4. Administer the medication with an antacid.
    5. Instruct the client to avoid exposure to the sun.
    6. Administer the medication on an empty stomach.
    • 2. Monitor liver function studies.
    • 3. Instruct the client to avoid alcohol.
    • 5. Instruct the client to avoid exposure to the sun.
  4. The nurse is caring for a client who has been taking a sulfonamide and should monitor for signs/symptoms of which side/adverse effects of the medication? Select all that apply.
    1. Ototoxicity
    2. Palpitations
    3. Nephrotoxicity
    4. Bone marrow depression
    5. Gastrointestinal (GI) effects
    6. Increased white blood cell (WBC) count
    • 3. Nephrotoxicity
    • 4. Bone marrow depression
    • 5. Gastrointestinal (GI) effects
  5. The nurse is reviewing the results of serum laboratory studies drawn on a client with acquired immunodeficiency syndrome who is receiving didanosine (Videx). The nurse interprets that the client may have the medication discontinued by the health care provider if which elevated result is noted?
    1. Serum protein level
    2. Blood glucose level
    3. Serum amylase level
    4. Serum creatinine level
    3. Serum amylase level
  6. The nurse is caring for a postrenal transplantation client taking cyclosporine (Sandimmune). The nurse notes an increase in one of the client's vital signs and the client is complaining of a headache. What vital sign is most likely increased?
    1. Pulse
    2. Respirations
    3. Blood pressure
    4. Pulse oximetry
    3. Blood pressure
  7. Amikacin (Amikin) is prescribed for a client with a bacterial infection. The nurse instructs the client to contact the health care provider (HCP) immediately if which occurs?
    1. Nausea
    2. Lethargy
    3. Hearing loss
    4. Muscle aches
    3. Hearing loss
  8. The nurse is assigned to care for a client with cytomegalovirus retinitis and acquired immunodeficiency syndrome who is receiving foscarnet, an antiviral medication. The nurse should monitor the results of which laboratory study while the client is taking this medication?
    1. CD4 cell count
    2. Lymphocyte count
    3. Serum albumin level
    4. Serum creatinine level
    4. Serum creatinine level
  9. A client who is human immunodeficiency virus seropositive has been taking stavudine (d4T, Zerit). The nurse should monitor which most closely while the client is taking this medication?
    1. Gait
    2. Appetite
    3. Level of consciousness
    4. Gastrointestinal function
    1. Gait
  10. The nurse is caring for a client with leukemia who has cytomegalovirus retinitis and is receiving foscarnet (Foscavir). Which assessment finding, if reported by the client, indicates a need for follow-up?
    1. Intact hearing capacity
    2. Urine noted to be clear yellow
    3. Urinary output of 30 mL per hour
    4. Impaired balance while ambulating
    4. Impaired balance while ambulating
  11. The client with acquired immunodeficiency syndrome (AIDS) has been prescribed raltegravir (Isentress). The nurse determines that the client may be experiencing an adverse effect related to this medication if which assessment finding is noted?
    1. Itching sensation
    2. Nausea and diarrhea
    3. Headache and fatigue
    4. Temperature of 101.2° F
    4. Temperature of 101.2° F
  12. The nurse is caring for a client with acquired immunodeficiency syndrome (AIDS) who is receiving Didanosine (Videx). The nurse understands that adverse effects associated with this medication include which findings? Select all that apply.
    1. Fatigue
    2. Diarrhea
    3. Pancreatitis
    4. Lactic acidosis
    5. Peripheral neuropathy
    • 2. Diarrhea
    • 3. Pancreatitis
    • 4. Lactic acidosis
    • 5. Peripheral neuropathy
  13. A client is taking brompheniramine maleate (BroveX). The nurse assesses for which side effect of this medication?
    1. Diarrhea
    2. Drowsiness
    3. Excitability
    4. Excess salivation
    2. Drowsiness
  14. Intravenous (IV) antithymocyte globulin (Atgam) is prescribed to a client for treatment of transplant rejection. Which intervention is the priority in planning the administration of this medication?
    1. Assess bowel sounds.
    2. Assess the neurovascular status.
    3. Plan for a skin test dose to identify hypersensitivity.
    4. Premedicate the client with acetylsalicylic acid (aspirin).
    3. Plan for a skin test dose to identify
  15. Tacrolimus (Prograf) is prescribed to a client for prevention of organ rejection after renal transplantation. Which prescription should the nurse anticipate to be prescribed, along with the tacrolimus, for this client?
    1. Prednisone
    2. Phenytoin (Dilantin)
    3. Fluconazole (Diflucan)
    4. Erythromycin (Erythrocin)
    1. Prednisone
  16. The nurse is monitoring a client receiving muromonab-CD3 (Orthoclone OKT3). Which finding is a priority assessment required in monitoring for adverse effects of this medication?
    1. Assessing pedal pulses
    2. Assessing lung sounds
    3. Assessing for pain in the calf
    4. Assessing for positive bowel sounds
    2. Assessing lung sounds
  17. Azathioprine (Imuran) is prescribed for a client to suppress rejection of a renal transplant. In planning for administration of the medication, the nurse understands that which description is the mechanism of action of this medication?
    1. It cross-links DNA.
    2. It blocks all T-cell functions.
    3. It inhibits the proliferation of B and T lymphocytes.
    4. It decreases the activity of thymus-derived lymphocytes.
    3. It inhibits the proliferation of B and T lymphocytes.
  18. A client who is receiving nitrofurantoin (Macrodantin) calls the clinic complaining of side effects related to the medication. Which side effect indicates the need to stop treatment with this medication?
    1. Nausea
    2. Anorexia
    3. Diarrhea
    4. Cough and chest pain
    4. Cough and chest pain
  19. Itraconazole (Sporanox) is prescribed for a client with a fungal infection of the hands. A nurse provides instructions to the client about the medication. Which statement by the client indicates an understanding of the instructions?
    1. "I should take the medication on an empty stomach."
    2. "I should decrease my fluid intake while taking the medication."
    3. "I may become unusually fatigued while taking this medication."
    4. "If my urine becomes very dark in color, I should contact my health care provider (HCP)."
    4. "If my urine becomes very dark in color, I should contact my health care provider (HCP)."
  20. Kanamycin sulfate (Kantrex), given by intermittent intravenous infusion, is prescribed for a client with a respiratory tract infection. Which finding would indicate to the nurse that the client is experiencing an adverse effect of the medication?
    1. Visual disturbances
    2. Gastrointestinal disturbances
    3. Decreased blood urea nitrogen (BUN)
    4. Elevated white blood cell (WBC) count
    1. Visual disturbances
  21. The nurse is providing discharge instructions to the mother of a child who has been prescribed tetracycline hydrochloride. The nurse stresses to the mother the importance of which measure in giving this medication to the child?
    1. Give the medication with milk.
    2. Use a straw when giving the medication.
    3. Give the medication with chocolate milk.
    4. Dilute the medication with water in a Styrofoam cup.
    2. Use a straw when giving the medication.
  22. A client with acquired immunodeficiency syndrome who is taking zidovudine (Retrovir) 200 mg orally three times daily has severe neutropenia noted on follow-up laboratory studies. The nurse interprets that which change is likely to occur at this point?
    1. The medication dose probably will be reduced.
    2. Prednisone probably will be added to the medication regimen.
    3. Epoetin alfa (Epogen) probably will be added to the medication regimen.
    4. The medication probably will be discontinued until laboratory results indicate bone marrow recovery.
    4. The medication probably will be discontinued until laboratory results indicate bone marrow recovery.
  23. A client with acquired immunodeficiency syndrome experiences nausea, vomiting, and abdominal pain radiating to the back after taking didanosine (Videx). The ambulatory care nurse should provide which response as telephone advice to this client?
    1. "Take crackers and milk with each dose of the medication."
    2. "Decrease the dose of the medication until the next clinic visit."
    3. "This is an uncomfortable but expected side effect of the medication."
    4. "Report to the health care clinic to be seen by the health care provider (HCP)."
    4. "Report to the health care clinic to be seen by the health care provider (HCP)."
  24. A client with acquired immunodeficiency syndrome is taking zalcitabine. The nurse interprets that the client is experiencing an adverse effect of this medication if which is reported by the client?
    1. Diarrhea
    2. Ringing in the ears
    3. Burning with urination
    4. Numbness or burning sensations in the arms or legs
    4. Numbness or burning sensations in the arms or legs
  25. A client with human immunodeficiency virus infection is taking indinavir (Crixivan). The nurse plans to provide the client with which direction when providing instructions about the use of this medication?
    1. Store the medication in the refrigerator.
    2. Take the medication with a high-fat snack.
    3. Take the medication with the large meal of the day.
    4. Take the medication with water on an empty stomach.
    4. Take the medication with water on an empty stomach.
  26. A client is receiving acyclovir (Zovirax) by the intravenous (IV) route for treatment of cytomegalovirus infection. After reconstituting the powder dispensed by the pharmacy, the nurse should administer this medication via which method?
    1. Slow IV infusion over 1 hour
    2. Rapid IV bolus over 5 minutes
    3. Continuous IV infusion over 24 hours
    4. Continuous IV infusion over 12 hours
    1. Slow IV infusion over 1 hour
  27. The nurse is monitoring a client with herpes simplex virus who is receiving intravenous (IV) acyclovir (Zovirax). Which laboratory result would be of concern as a possible adverse effect of this medication?
    1. Platelet count of 300,000 cells/mm3
    2. Blood urea nitrogen (BUN) of 36 mg/dL
    3. White blood cell count of 6000 cells/mm3
    4. Red blood cell count of 5.2 million cells/mm3
    2. Blood urea nitrogen (BUN) of 36 mg/dL
  28. A pediatric nurse has obtained ribavirin (Virazole) in powder form from the pharmacy to administer to a child with respiratory syncytial virus (RSV) infection. After preparing the medication, the nurse should administer it by which route?
    1. Inhalation
    2. Intravenous
    3. Subcutaneous
    4. Oral, in the formula
    1. Inhalation
  29. A client with candidiasis is receiving amphotericin B by the intravenous route (IV). The nurse determines that the client is having an adverse effect to the medication if which laboratory study result is noted?
    1. Elevated platelet count
    2. Elevated serum creatinine
    3. Low white blood cell count
    4. Lowered hemoglobin and hematocrit
    2. Elevated serum creatinine
  30. A client who has been diagnosed with pneumonia has been given a prescription for erythromycin (E-mycin). Client teaching about this medication should include which best instruction?
    1. Take the medication with juice.
    2. Take the medication with a meal.
    3. Take the medication on an empty stomach.
    4. Take the medication at bedtime with a snack.
    3. Take the medication on an empty stomach.
  31. A client has been diagnosed with chlamydial infection, and azithromycin (Zithromax) has been prescribed. The nurse should instruct the client to take the medication in which way?
    1. With meals
    2. 1 hour before meals
    3. With an aluminum-containing antacid
    4. With a magnesium-containing antacid
    2. 1 hour before meals
  32. The nurse is collecting subjective and objective data from a client and notes that the client is taking abacavir (Ziagen). The nurse determines that this medication has been prescribed to treat which condition?
    1. Otitis media
    2. Heart failure
    3. Urinary tract infection
    4. Human immunodeficiency virus (HIV) infection
    4. Human immunodeficiency virus (HIV) infection
  33. The home care nurse is visiting a client with a skin infection who is receiving amoxicillin (Amoxil) orally every 8 hours. Which finding would indicate to the nurse that the client is experiencing a frequent side effect related to the medication?
    1. Fever
    2. Vaginal drainage
    3. Severe watery diarrhea
    4. Severe abdominal cramps
    2. Vaginal drainage
  34. The nurse is developing a plan of care for a client who is receiving amphotericin B intravenously to treat a severe fungal infection. A main component of the plan of care is monitoring for adverse effects related to the administration of this medication. Which should the nurse include in a list of manifestations to watch for?
    1. Fatigue
    2. Confusion
    3. Visual difficulties
    4. Increased urinary output
    3. Visual difficulties
  35. A client with disseminated candidiasis has a prescription for amphotericin B by the intravenous (IV) route. During ongoing therapy with this medication, the nurse should most closely assess the client for which finding that indicates a complication?
    1. Decreased pulse
    2. Decreased urine output
    3. Decreased body temperature
    4. Decreased blood urea nitrogen level
    2. Decreased urine output
  36. The nurse is providing discharge instructions to a client who will be taking tacrolimus (Prograf) daily following allogenic liver transplantation. The nurse instructs the client that which is a frequent side effect related to this medication?
    1. Diarrhea
    2. Confusion
    3. Loss of memory
    4. A decrease in urine output
    1. Diarrhea
  37. Tobramycin sulfate is prescribed for a client with a diagnosis of cellulitis. The nurse is administering the medication by intermittent intravenous infusion every 8 hours. The nurse monitors the client for signs of an adverse effect related to this medication and determines that which, if noted on assessment, would indicate the presence of an adverse effect?
    1. Client complaint of diarrhea
    2. Client complaint of ringing in the ears
    3. A blood urea nitrogen (BUN) of 10 mg/dL
    4. A white blood cell count of 6000 cells/mm3
    2. Client complaint of ringing in the ears
  38. A client is receiving ganciclovir to treat acquired immunodeficiency syndrome and cytomegalovirus retinitis. Which nursing action is appropriate during the time the client is receiving this medication?
    1. Monitoring blood glucose levels for elevation
    2. Administering the medication on an empty stomach only
    3. Applying pressure to venipuncture sites for at least 1 minute
    4. Providing the client with a soft toothbrush and an electric razor
    4. Providing the client with a soft toothbrush and an electric razor
  39. A client has been receiving foscarnet sodium as part of therapy for the treatment of cytomegalovirus retinitis and acquired immunodeficiency syndrome (AIDS). The home care nurse should periodically review results of which laboratory blood test to assess for adverse effects to this medication?
    1. CD4+ cell count
    2. Lymphocyte count
    3. Albumin concentration
    4. Creatinine concentration
    4. Creatinine concentration
  40. A health care provider has just prescribed foscarnet (Foscavir) to be given intravenously to a client with acquired immunodeficiency syndrome (AIDS). The nurse should obtain which piece of equipment to administer this medication?
    1. A glass bottle
    2. An infusion pump
    3. A microdrip tubing set
    4. Special manufacturer's tubing
    2. An infusion pump
  41. Quinupristin-dalfopristin (Synercid) is prescribed as an intermittent intravenous (IV) infusion for a client with a skin infection. The nurse should adjust the drip rate so that the dose is administered over what period of time?
    1. 1 hour
    2. 4 hours
    3. 15 minutes
    4. 30 minutes
    1. 1 hour
  42. A client is scheduled to receive a first dose of pentamidine (Pentam 300) intravenously. What should the nurse plan to carefully monitor as the priority during administration of the first dose?
    1. Pulse rate
    2. Breath sounds
    3. Blood pressure
    4. Respiratory rate
    3. Blood pressure
  43. A client has been given a prescription for a course of azithromycin (Zithromax). The nurse should tell the client that this medication will relieve which problem?
    1. Pain
    2. Joint inflammation
    3. High blood pressure
    4. Signs and symptoms of infection
    4. Signs and symptoms of infection
  44. A client with a respiratory tract infection is receiving intravenous tobramycin sulfate (Tobrex). The nurse should assess for which adverse effect of this medication?
    1. Nausea
    2. Vertigo
    3. Vomiting
    4. Hypotension
    2. Vertigo
  45. A nurse is caring for a client with a urinary tract infection. The culture report reveals the presence of Pseudomonas aeruginosa. The nurse anticipates that which medication will be prescribed to treat the infection?
    1. Isoniazid
    2. Rifampin (Rifadin)
    3. Ciprofloxacin (Cipro)
    4. Ethambutol (Myambutol)
    3. Ciprofloxacin (Cipro)
  46. The home health nurse is visiting a client who has been started on therapy with clotrimazole (Lotrimin AF). The nurse should monitor which item to monitor the effectiveness of this medication with each visit?
    1. Rash
    2. Fever
    3. Pain relief
    4. Sore throat
    1. Rash
  47. Levofloxacin (Levaquin) is prescribed for a client with gonorrhea. While teaching the client about the medication, what should the nurse tell the client to take the medication with?
    1. Water
    2. An antacid
    3. A zinc preparation
    4. An iron supplement
    1. Water
  48. A child with human immunodeficiency virus (HIV) infection is receiving zidovudine (ZDV). The nurse monitors which laboratory study to determine whether the child is experiencing an adverse effect from the medication?
    1. Serum calcium level
    2. Serum potassium level
    3. Complete blood cell (CBC) count
    4. Erythrocyte sedimentation rate (ESR)
    3. Complete blood cell (CBC) count
  49. The clinic nurse is providing medication instructions to a client who will be receiving hydroxychloroquine sulfate (Plaquenil) to treat systemic lupus erythematosus. The nurse instructs the client about the importance of returning to the clinic in 6 months for which follow-up test?
    1. Sigmoidoscopy
    2. Eye examination
    3. Chest radiograph
    4. Dental examination
    2. Eye examination
  50. Pyrimethamine (Daraprim) has been added to the medication regimen for a client with acquired immunodeficiency syndrome. On review of the client's record, the nurse notes this new prescription and plans care knowing that it has been prescribed to treat which condition?
    1. Toxoplasmosis
    2. Kaposi's sarcoma
    3. Cardiac irregularities
    4. Nausea and vomiting
    1. Toxoplasmosis
  51. Dapsone is prescribed to treat toxoplasmosis in a client with acquired immunodeficiency syndrome. The nurse reinforces medication instructions and tells the client to perform which action?
    1. Report to the clinic weekly for the injections.
    2. Plan to take the medication every 6 hours around the clock.
    3. Discontinue the medication if nausea and vomiting develop.
    4. Contact the health care provider (HCP) if fever or a sore throat occurs.
    4. Contact the health care provider (HCP) if fever or a sore throat occurs.
  52. Cyclosporine (Sandimmune) is prescribed for a client who received a kidney transplant. The nurse would be most concerned if a review of the medical record revealed that the client currently is taking which prescribed medications?
    1. Prednisone
    2. Digoxin (Lanoxin)
    3. Propranolol (Inderal)
    4. Phenytoin (Dilantin)
    4. Phenytoin (Dilantin)
  53. Cyclosporine (Sandimmune) is prescribed to be administered by the intravenous (IV) route. Which option indicates an inappropriate action in regard to preparing and administering this medication?
    1. Mixing the solution and covering it with a paper bag
    2. Administering the medication over a period of 2 to 6 hours
    3. Mixing 1 mL of concentrate in 50 mL of 0.9% sodium chloride and administering by infusion
    4. Mixing 1 mL of concentrate in 10 mL of 0.9% sodium chloride and administering by bolus injection
    4. Mixing 1 mL of concentrate in 10 mL of 0.9% sodium chloride and administering by bolus injection
  54. Muromonab-CD3 (Orthoclone OKT3) is prescribed for a client to manage allograft rejection after renal transplantation. The nurse plans care, knowing that the primary mechanism of action of this medication is what?
    1. Suppresses B lymphocytes
    2. Inhibits the proliferation of B lymphocytes
    3. Cross-links DNA, causing cell injury and death
    4. Binds to the CD3 site and blocks all T-cell functions
    4. Binds to the CD3 site and blocks all T-cell functions
  55. The nurse is preparing to administer a prescribed dose of cyclosporine (Sandimmune) by intravenous (IV) administration. Which priority item would the nurse have available during administration of this medication?
    1. A code cart
    2. Oral airway
    3. A suction catheter
    4. Epinephrine (Adrenalin)
    4. Epinephrine (Adrenalin)
  56. A client taking an antihistamine is scheduled for allergy skin testing and tells the nurse in the health care provider's office that a dose was taken this morning. The nurse interprets this to mean that which adjustment needs to be made?
    1. A lower dose of allergen should be injected.
    2. A higher dose of allergen should be injected.
    3. The client should reschedule the appointment.
    4. The client should have the skin test read a day later than usual.
    3. The client should reschedule the appointment.
  57. Abacavir succinate (Ziagen) has been prescribed for a client, and the client asks the nurse about the action of the medication. How should the nurse respond?
    1. Promotes viral DNA growth
    2. Prevents the production of DNA
    3. Splits DNA to prevent its production
    4. Inhibits activity of HIV-1 reverse transcriptase
    4. Inhibits activity of HIV-1 reverse transcriptase
  58. Abacavir (Ziagen) has been prescribed for a client. The nurse tells the client that which blood test will be done periodically while the client is taking this medication?
    1. Platelet count
    2. Liver function tests
    3. Serum creatinine assay
    4. Blood urea nitrogen determination
    2. Liver function tests
  59. Abacavir (Ziagen) has been prescribed for a client, who asks the nurse about the side effect of the medication. What should the nurse tell the client is a frequent side effect of this medication?
    1. Nausea
    2. Sleepiness
    3. Constipation
    4. Increased appetite
    1. Nausea
  60. A client admitted to the hospital is taking abacavir (Ziagen). The nurse should monitor the client for which adverse effect of the medication?
    1. Insomnia
    2. Diarrhea
    3. Hypotension
    4. Decreased appetite
    3. Hypotension
  61. Abacavir (Ziagen) has been prescribed for a client, and the nurse provides instructions about the medication. Which statement by the client indicates the need for further instruction?
    1. "This medication will not cure my infection."
    2. "Eating small, frequent meals will help offset the nausea."
    3. "This medication will reduce the risk of transmitting the infection to others."
    4. "I should check with my health care provider before taking any over-the-counter medications."
    3. "This medication will reduce the risk of transmitting the infection to others."
  62. The nurse is collecting subjective and objective data from a client and notes that the client is taking zidovudine (Retrovir). The nurse determines that this medication has been prescribed to treat which condition?
    1. Ulcerative colitis
    2. Hyperthyroidism
    3. Addison's disease
    4. Human immunodeficiency virus (HIV) infection
    4. Human immunodeficiency virus (HIV) infection
  63. Zidovudine (Retrovir) has been prescribed for a client who asks the nurse about the action of the medication. The nurse responds that this medication performs which function?
    1. Increases neutrophils
    2. Kills bacteria and fungi
    3. Promotes the function of natural killer cells
    4. Slows the replication of human immunodeficiency virus (HIV)
    4. Slows the replication of human immunodeficiency virus (HIV)
  64. A client seen in the health care clinic is diagnosed with syphilis, and the health care provider prescribes an intramuscular injection of penicillin G benzathine (Bicillin). After administering the intramuscular injection of medication, the nurse should perform which action?
    1. Monitor the client for 30 minutes.
    2. Encourage the client to ambulate.
    3. Administer subcutaneous epinephrine.
    4. Apply a topical anesthetic spray to the injection site.
    1. Monitor the client for 30 minutes.
  65. Azithromycin (Zithromax) is prescribed for a client with a respiratory tract infection. The nurse provides instructions to the client about the medication and emphasizes that it is bestto take the medication with which item?
    1. Milk
    2. Antacid
    3. The evening meal
    4. Water on an empty stomach
    4. Water on an empty stomach
  66. The health care provider (HCP) writes a prescription for zidovudine (Retrovir) for a client who was admitted to the hospital. The nurse should contact the HCP to verify the prescription if which finding is noted in the assessment data?
    1. History of renal calculi
    2. Complaints of diarrhea
    3. Bone marrow depression
    4. Complaints of abdominal discomfort
    3. Bone marrow depression
  67. Zidovudine (Retrovir) has been prescribed for a client. The nurse should tell the client that which blood test will be done periodically while the client is taking this medication?
    1. Potassium level determination
    2. Magnesium level determination
    3. Complete blood cell count (CBC)
    4. Sedimentation rate determination
    3. Complete blood cell count (CBC)
  68. Zidovudine (Retrovir) has been prescribed for a client, and the client asks the nurse about the side effects of the medication. The nurse responds that which is a common side effect of this medication?
    1. Lethargy
    2. Weakness
    3. Headache
    4. Constipation
    3. Headache
  69. A client admitted to the hospital is taking zidovudine (Retrovir). The nurse monitors the client for which adverse effect of the medication?
    1. Colitis
    2. Ototoxicity
    3. Neurotoxicity
    4. Visual disturbances
    3. Neurotoxicity
  70. Zidovudine (Retrovir) has been prescribed for a client, and the nurse provides instructions to the client about expected effects with this medication. Which statement by the client indicates the need for further instruction?
    1. "I need to monitor my temperature."
    2. "This medication can cause some nausea."
    3. "I will have to have blood tests done periodically."
    4. "If I experience diarrhea, I need to contact my health care provider (HCP)."
    4. "If I experience diarrhea, I need to contact my health care provider (HCP)."
  71. A nurse has a prescription to administer foscarnet sodium intravenously to a client with acquired immunodeficiency syndrome (AIDS). What should the nurse plan to do before administering this medication?
    1. Obtain a sputum culture.
    2. Obtain folic acid (Folvite) as an antidote.
    3. Place the solution on a controlled infusion pump.
    4. Ensure that liver enzyme levels have been drawn as a baseline.
    3. Place the solution on a controlled infusion pump.
  72. The nurse is about to administer an intravenous dose of tobramycin when the client complains of vertigo and a ringing in the ears. What is the most appropriate nursing action?
    1. Hang the dose immediately.
    2. Check the client's pupillary responses.
    3. Give a dose of droperidol with the tobramycin.
    4. Withhold the dose and call the health care provider (HCP).
    4. Withhold the dose and call the health care provider (HCP).
  73. The nurse is caring for a client diagnosed with a skin infection. The client is receiving tobramycin sulfate intravenously every 8 hours. Which finding would indicate to the nurse that the client is experiencing an adverse medication effect?
    1. A sedimentation rate of 15 mm/hr
    2. A total bilirubin level of 0.5 mg/dL
    3. A white blood cell count of 6000 cells/mm3
    4. A blood urea nitrogen (BUN) level of 30 mg/dL
    4. A blood urea nitrogen (BUN) level of 30 mg/dL
  74. A client has been given a prescription for sulfasalazine (Azulfidine) for the treatment of ulcerative colitis. Which allergy should the nurse assess for in the client prior to administration?
    1. Sulfonamides or salicylates
    2. Salicylates or acetaminophen
    3. Shellfish or calcium channel blockers
    4. Histamine receptor antagonists or β-blockers
    1. Sulfonamides or salicylates
  75. A client receiving a dose of intravenous vancomycin (Vancocin) begins to experience chills, tachycardia, syncope, and flushing of the face and trunk. What is the nurse's best interpretation of these findings?
    1. The medication is infusing too rapidly.
    2. The client is allergic to the medication.
    3. The client is experiencing upper airway obstruction.
    4. The medication has interacted with another medication the client is receiving.
    1. The medication is infusing too rapidly.
  76. A client is receiving tobramycin (Tobrex). The nurse evaluates that the medication therapy iseffective if which laboratory test result is noted?
    1. Sodium level of 145 mEq/L and chloride level of 106 mEq/L
    2. Sodium level of 140 mEq/L and potassium level of 3.9 mEq/L
    3. WBC count of 15,000 cells/mm3 and a blood urea nitrogen level of 38 mg/dL
    4. White blood cell (WBC) count of 8000 cells/mm3 and creatinine level of 0.9 mg/dL
    4. White blood cell (WBC) count of 8000 cells/mm3 and creatinine level of 0.9 mg/dL
  77. A client with histoplasmosis has a prescription for ketoconazole. Which instruction should the nurse include in the client's teaching plan?
    1. Avoid exposure to sunlight.
    2. Take the medication with an antacid.
    3. Take the medication on an empty stomach.
    4. Limit alcohol consumption to 2 ounces per day.
    1. Avoid exposure to sunlight.
  78. A 2-year-old with Pneumocystis jiroveci pneumonia is to begin treatment with highly active antiretroviral therapy (HAART). The nurse anticipates that the health care provider will prescribe which combination?
    1. One immunoglobulin and one nucleoside analogue
    2. Two nucleoside analogues and one protease inhibitor
    3. Two protease inhibitors and one broad-spectrum antibiotic
    4. One nucleoside reverse transcriptase inhibitor and one non-nucleoside reverse transcriptase inhibitor
    2. Two nucleoside analogues and one protease inhibitor
  79. A nurse provides instructions to a client who will be taking cyclosporine (Sandimmune) oral solution. Which action should nurse tell the client to do?
    1. Mix the concentrate with orange juice.
    2. Mix the concentrate with grapefruit juice.
    3. Avoid diluting the concentrate for administration.
    4. Dilute the concentrate in a Styrofoam cup before administration.
    1. Mix the concentrate with orange juice.
  80. A nurse is monitoring a client receiving cyclosporine (Sandimmune). Which sign or symptom should indicate to the nurse that the client is experiencing an adverse effect from this medication?
    1. Nausea
    2. Tremors
    3. Alopecia
    4. Hypotension
    2. Tremors
  81. Mycophenolate mofetil (CellCept) is prescribed for a client for prophylaxis of organ rejection following allogenic renal transplantation. Which instruction should the nurse provide to the client regarding administration of this medication?
    1. Administer following meals.
    2. Take the medication with a magnesium-type antacid.
    3. Open the capsule and mix with food for administration.
    4. Contact the health care provider (HCP) if a sore throat occurs.
    4. Contact the health care provider (HCP) if a sore throat occurs.
  82. A client is diagnosed with herpes simplex type 1. The health care provider prescribes a topical medication for treatment. The nurse anticipates that which medication will be prescribed?
    1. Salicylic acid
    2. Gentamicin sulfate
    3. Acyclovir (Zovirax)
    4. Mupirocin calcium (Bactroban)
    3. Acyclovir (Zovirax)
  83. An outbreak of pediculosis capitus has occurred at a local school. The school nurse is providing instructions to the parents of the children attending the school regarding the application of permethrin (Nix). Which action should the nurse tell the parents to take?
    1. Apply permethrin before washing the hair.
    2. Apply permethrin at bedtime and rinse it off in the morning.
    3. Avoid saturating the hair and scalp when applying permethrin.
    4. Allow permethrin to remain on the hair 10 minutes and then rinse with water.
    4. Allow permethrin to remain on the hair 10 minutes and then rinse with water.
  84. The nurse is caring for a client with a diagnosis of Chlamydia. Because the client has a history of noncompliance with medication administration, the health care provider prescribes azithromycin (Zithromax). When educating the client about azithromycin, the nurse should make which statement?
    1. "One dose of this medication will be needed."
    2. "This medication is only given every 72 hours."
    3. "You will need to take this medication every 6 hours."
    4. "You will need to return tomorrow for your second dose."
    1. "One dose of this medication will be needed."
  85. A client with a severe allergic reaction is prescribed intravenous corticosteroids. The nurse should expect that which desired effect will be achieved?
    1. Decreased inflammation
    2. Increased serum glucose
    3. Enhanced immunity
    4. Pain relief
    1. Decreased inflammation
  86. A nurse is caring for a client receiving gentamicin intravenously. What statement made by the client should most concern the nurse?
    1. "I am experiencing dizziness."
    2. "I am experiencing heartburn."
    3. "I am experiencing abdominal pain."
    4. "I am experiencing ringing in my ears."
    4. "I am experiencing ringing in my ears."
  87. A nurse is caring for a client admitted to the hospital for an infection who is receiving an aminoglycoside twice a day, intravenously. The nurse is planning to obtain blood for a peak aminoglycoside level. When should the blood be drawn?
    1. A peak level is not indicated.
    2. 1 hour after completing the infusion
    3. 1 hour before administration of the infusion
    4. 15 minutes before administration of the infusion
    2. 1 hour after completing the infusion
  88. A nurse is preparing to administer ticarcillin. An abnormal elevation in which laboratory value should prompt the nurse to withhold the medication and notify the health care provider before administering the medication?
    1. Hematocrit and hemoglobin
    2. Blood urea nitrogen and creatinine
    3. Prothrombin time and partial thromboplastin time
    4. Aspartate aminotransferase and alanine transaminase
    2. Blood urea nitrogen and creatinine
  89. The nurse is presenting information regarding treatment of influenza and the use of oseltamivir (Tamiflu). The nurse should provide which information regarding the use of Tamiflu? Select all that apply.
    1. Tamiflu is effective for all types of influenza.
    2. The incidence of flu complications is reduced.
    3. Dosing must begin within 2 days after symptom onset.
    4. No interactions with other medications have been reported.
    5. It is best to begin dosing within the first 12 hours after symptom onset.
    6. Tamiflu is highly toxic to the liver, and liver function studies must be performed.
    • 1. Tamiflu is effective for all types of influenza.
    • 2. The incidence of flu complications is reduced.
    • 3. Dosing must begin within 2 days after symptom onset.
    • 4. No interactions with other medications have been reported.
    • 5. It is best to begin dosing within the first 12 hours after symptom onset.
  90. The nurse asks the student nurse, "What does it mean that an antibiotic is classified as a bactericidal agent?" Which response by the nursing student indicates an understanding of a bactericidal agent?
    1. Has low efficacy
    2. Has a very low potency
    3. Kills the infectious agent
    4. Slows the growth of the infectious agent
    3. Kills the infectious agent
  91. A client asks the nurse why the health care provider (HCP) changed to a different antibiotic for treating streptococcal throat infection. The nurse should make which bestresponse?
    1. "Antibiotics all have the same method of action."
    2. "You probably misunderstood what the health care provider (HCP) said."
    3. "Try this medicine, and if you're not better in 5 to 7 days, return to the office."
    4. "Bacteria are capable of developing resistance to frequently used antibiotics."
    4. "Bacteria are capable of developing resistance to frequently used antibiotics."
  92. The nurse understands that which is correct about tetracycline (Sumycin)?
    1. It is classified as a narrow-spectrum antibiotic.
    2. It is identified as safe for use during pregnancy.
    3. It is used to treat a wide variety of disease processes.
    4. It is contraindicated in children younger than 8 years of age.
    4. It is contraindicated in children younger than 8 years of age.
  93. A nurse reviews the medication history of a client and notes that the client is taking leflunomide (Arava). During assessment of the client, the nurse should ask which question to determine the effectiveness of this medication?
    1. "Do you have any joint pain?"
    2. "Are you having any diarrhea?"
    3. "Are you experiencing heartburn?"
    4. "Do you have frequent headaches?"
    1. "Do you have any joint pain?"
  94. The nurse notes that a client is receiving lamivudine (Epivir). The nurse determines that this medication has been prescribed to treat which condition?
    1. Pancreatitis
    2. Pharyngitis
    3. Tonic-clonic seizures
    4. Human immunodeficiency virus (HIV)
    4. Human immunodeficiency virus (HIV)
  95. A nurse reinforces medication instructions to a client who has received a kidney transplant about therapy with cyclosporine (Sandimmune). Which statement by the client would indicate a need for further instruction?
    1. "I need to obtain a yearly influenza vaccine."
    2. "I need to have dental checkups every 3 months."
    3. "I need to self-monitor my blood pressure at home."
    4. "I need to call the health care provider if my urine volume decreases or it becomes cloudy."
    1. "I need to obtain a yearly influenza vaccine."
  96. A client who has received a kidney transplant is taking azathioprine (Imuran), and the nurse provides instructions about the medication. Which statement by the client would indicate a need for further instruction?
    1. "I need to watch for signs of infection."
    2. "I need to discontinue the medication after 14 days of use."
    3. "I can take the medication with meals to minimize nausea."
    4. "I need to call the health care provider if more than one dose is missed."
    2. "I need to discontinue the medication after 14 days of use."
  97. A pregnant client who has human immunodeficiency virus (HIV) infection is being seen in the antenatal clinic. The nurse recalls that zidovudine (AZT) therapy will be initiated when the fetus has reached how many weeks of gestation?
    1. 4
    2. 14
    3. 24
    4. 34
    2. 14
  98. A child has been prescribed to take tetracycline hydrochloride. The nurse providing medication information to the mother should plan to emphasize which instruction about giving this medication to the child?
    1. Give the medication with milk.
    2. Give the medication with ice cream.
    3. Mix the medication in a Styrofoam cup.
    4. Use a straw when giving the medication.
    4. Use a straw when giving the medication.
  99. A client with a urinary tract infection (UTI) has been prescribed to take ciprofloxacin (Cipro). The nurse notes that the client also has a prescription for theophylline written by a pulmonologist. Based on this information, the nurse should take which action?
    1. Encourage intake of antacids.
    2. Clarify the medication prescriptions.
    3. Schedule the doses to be given together.
    4. Schedule the doses to be given at the same time.
    2. Clarify the medication prescriptions.
  100. A client who has undergone renal transplant is receiving ongoing therapy with cyclosporine (Sandimmune). The nurse would be sure to immediately report which abnormal finding?
    1. Decreased creatinine level
    2. Decreased hemoglobin level
    3. Decreased white blood cell (WBC) count
    4. Elevated blood urea nitrogen (BUN) level
    4. Elevated blood urea nitrogen (BUN) level
  101. A client is receiving tacrolimus (Prograf) to prevent organ rejection. Which is a nursing consideration associated with this medication?
    1. Assess for hypoglycemia.
    2. Give with grapefruit juice.
    3. Give with cyclosporine (Sandimmune).
    4. Assess platelet count for thrombocytopenia.
    4. Assess platelet count for thrombocytopenia.
  102. A client must begin medication therapy with mycophenolate mofetil (CellCept) to prevent organ rejection following renal transplantation. The nurse should provide which important teaching point to the client?
    1. Take the dose following meals.
    2. Open the capsule and mix with food before use.
    3. Take the medication with an aluminum-based antacid.
    4. Notify the health care provider (HCP) if a fever develops.
    4. Notify the health care provider (HCP) if a fever develops.
  103. A nurse is collecting data from a client with a history of renal transplantation. The nurse understands that which medication is the medication of choice for preventing organ rejection?
    1. Probenecid
    2. Prednisone
    3. Indomethacin (Indocin)
    4. Cyclosporine (Sandimmune)
    4. Cyclosporine (Sandimmune)
  104. Cyclosporine (Sandimmune) is prescribed for the client following allogenic kidney transplantation. The nurse should provide which instruction to the client regarding the medication?
    1. There are no known adverse effects of the medication.
    2. The medication will need to be taken for a period of 6 months.
    3. Blood levels of the medication will need to be measured periodically.
    4. The medication is administered by the intravenous (IV) route on a monthly basis.
    3. Blood levels of the medication will need to be measured periodically.
  105. Blood work has been drawn on a client who has been taking cyclosporine (Sandimmune) following allogenic liver transplantation. The nurse should check the results of which test to determine the presence of an adverse effect related to this medication?
    1. Hematocrit level
    2. Cholesterol level
    3. Hemoglobin level
    4. Blood urea nitrogen (BUN) level
    4. Blood urea nitrogen (BUN) level
  106. Dapsone is prescribed for a client with acquired immunodeficiency syndrome (AIDS) for the treatment of toxoplasmosis. The nurse provides medication instructions and determines that the client understands the instructions if the client states that which action is necessary?
    1. Discontinue the medication if nausea develops.
    2. Report a sore throat to the health care provider (HCP).
    3. Plan to take the medication every 4 hours around the clock.
    4. Expect that abdominal pain and jaundice will occur as normal side effects.
    2. Report a sore throat to the health care provider (HCP).
  107. The client who is seropositive for human immunodeficiency virus (HIV) has been taking ritonavir (Norvir). The nurse tells the client that which follow-up laboratory study will be necessary while taking this medication?
    1. Platelet count
    2. Triglyceride level
    3. Prothrombin time (PT)
    4. International normalized ratio (INR)
    2. Triglyceride level
  108. A client who is seropositive for human immunodeficiency virus (HIV) has been taking stavudine (d4T, Zerit XR). The nurse assesses which most closely while the client is taking this medication?
    1. Appetite
    2. Presence of paresthesia
    3. Gastrointestinal function
    4. Level of consciousness (LOC)
    2. Presence of paresthesia
  109. A nurse is assigned to care for a client with cytomegalovirus retinitis and acquired immunodeficiency syndrome (AIDS) who is receiving foscarnet. The nurse reviews the health care provider's (HCP) prescriptions, expecting to note a prescription for which laboratory test while this client is taking the medication?
    1. CD4+ cell count
    2. Lymphocyte count
    3. Serum albumin level
    4. Serum creatinine level
    4. Serum creatinine level
  110. The client with acquired immunodeficiency syndrome (AIDS) and Pneumocystis jiroveci infection has been receiving pentamidine (Pentam 300). The nurse caring for the client should monitor the client most closely for signs of which adverse effect of the medication?
    1. Nausea
    2. Fatigue
    3. Vomiting
    4. Infection
    4. Infection
  111. The client with human immunodeficiency virus (HIV) infection has been started on therapy with zidovudine (Retrovir). The nurse reviews the health care provider's (HCP) prescriptions, expecting to note that which laboratory test has been prescribed?
    1. Blood culture
    2. Blood glucose level
    3. Blood urea nitrogen level (BUN)
    4. Complete blood cell count (CBC)
    4. Complete blood cell count (CBC)
  112. The nurse is preparing to administer pentamidine (Pentam 300) to an assigned client by the intravenous route. The nurse plans to monitor which item most closely after administering this medication?
    1. Capillary refill
    2. Peripheral pulses
    3. Blood pressure (BP)
    4. Level of consciousness
    3. Blood pressure (BP)
  113. Ketoconazole is prescribed for an assigned client. The nurse prepares to administer the medication by which method?
    1. With food
    2. With an antacid
    3. With 8 oz of water
    4. On an empty stomach
    1. With food

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