DIT pharm

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Author:
Neda317
ID:
294063
Filename:
DIT pharm
Updated:
2015-01-28 00:14:51
Tags:
Pharm
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Description:
DIT
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  1. MOA Amitriptyline
    inhibits NE reuptake
  2. Amphetamine MOA
    stimulated NE release
  3. Black widow spider toxin
    (+) Ach release
  4. Botulinum toxin
    (-) Ach release
  5. Bretylium MOA
    (-) NE release
  6. Cocaine
    (-) NE reuptake
  7. Guanethidine MOA
    (-) NE release
  8. Hemicholinium MOA
    (-) choline transport
  9. Reserpine MOA
    (-) NE packaging
  10. Vesamicol MOA
    (-) Ach packaging
  11. what inc NE release
    • Ca2+
    • amphetamine 
    • ephedrine 
    • tyramine
  12. Drugs w disulfiram-like reactions
    • Metronidazole
    • Certain Cephalosporins 
    • Procarbazine 
    • 1st gen sulfonylureas
  13. Methanol ---> ____ 
    reaction in body
    • Formaldehyde 
    • acidosis, retinal damage, blindness
  14. Ethylene glycol ---> ____
    reaction in body
    • oxalic acid 
    • acidosis, kidney damage, CNS problems, heart/lung toxicity
  15. tx of urge incontinence?
    • oxybutynin
    • tolterodine 
    • Darifenacin
    • solifenacin
    • trospium
  16. Formoterol what drug family?
    B2 agonist
  17. anti psych that causes NMS (neuroleptic malignant syndrome)
    chlorpromazine, haloperidol, and fluphenazine, can cause NMS
  18. tx of NMS
    dantrolene and dopamine agonists
  19. Ebstein's anomaly
    • associated w Lithium use during 1st trimester. 
    • Ebstein's anomaly is a rare congenital heart condition that is characterized by the deformity of the tricuspid valve with apical displacement (downward displacement) of the septal and posterior leaflets, causing them to adhere to the right ventricle wall. The right ventricle is thus divided into two parts: (1) the atrialized (thinned) part, which is the proximal part of the right ventricle that is now continuous with the enlarged right atrium, and (2) the functional right ventricle, which is a small chamber composed of the infundibular and apical portions of the right ventricle
  20. pt medication history is significant for a drug that inhibits dihydrofolate reductase (metatoraxate) .Co-administration of what drug could decrease this patient's adverse effects?
    leucovorin
  21. hep C tx
    Ribavirin inhibits inosine monophosphate dehydrogenase, thereby inhibiting nucleotide formation. It is used to treat hepatitis C. Ribavirin is associated with hemolytic anemia

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