Study EP2.6

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Author:
mame727
ID:
294128
Filename:
Study EP2.6
Updated:
2015-01-28 00:53:12
Tags:
genetics
Folders:
genetics
Description:
Genetics. Starting from Lecture 6.
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  1. What is Phylogeny?
    What are homologs?
    What are orthologs?
    What are paralogs?
    What is an out group?
    • Phylogeny is the evolutionary history of a group of species.
    • Homologs are the most closely related genes, second step in comparing genomes.

    Orthologs are homologs that have their genes at the same genetic locus in different species inherited from a common ancestor.

    Paralogs are homologous genes that are at different genetic loci in the same organism.

    An out group is out group used in a taxa that is outside the entire group of mammals used in phylogenetic inferences.
  2. What is Parsimony?
    When is it used?
    Parsimony is favoring the simplest explanation that is involving the smallest number of evolutionary changes.

    Parsimony is used when studying infrequent events such as the invention of a gene.
  3. What is a microarray?

    What are microarrays exposed to and what hybridize?

    What two things contribute to genome divergence?
    Microarray is the set of DNAs displayed in a glass "chip" or a DNA chip in where the DNA is laid out as a series of microscopic spots bound to the glass.

    cDNA probes with attached fluorescent labels that hybridize to the microarray.

    Changes in a particular genes and duplication of chromosome segments in a single lineage.

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