Skeletal Muscle

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Author:
fruitpunch
ID:
294132
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Skeletal Muscle
Updated:
2015-01-28 22:16:28
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muscles muscle skeletal myosin
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Skeletal muscle
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  1. Place the events of excitation contraction coupling in order from the action potential being produced at the neuromuscular junction to finish.
    a. Ca2+ diffuses out into the sarcoplasm
    b.Ca2+ release channels in SR open
    c. Action Potentials conducted along transverse tubules
    d. AP opens voltage gated Ca2+ channels in T-tubules
    e. Ca2+ binds to troponin beginning contraction
    • c. Action Potentials conducted along transverse tubules
    • d. AP opens voltage gated Ca2+ channels in T-tubules
    • b.Ca2+ release channels in SR open
    • a. Ca2+ diffuses out into the sarcoplasm
    • e. Ca2+ binds to troponin beginning contraction
  2. The general term for the activatin of the force-generating sites within muscle fibers, the cross-bridges, is called a(n) _____.
    contraction
  3. Which of the following actions apply to the myosin cross bridge heads?
    a) Part of the actin protein
    b)Part of the myosin protein
    c)Bind and pull on actin
    d)Bind to calcium and move tropomyosin
    • Part of the myosin protein, bind and pull on actin
    • b,c
  4. The specialized region of the sarcolemma of a muscle fiber at the neuromuscular junction is called _____.
    motor end plate
  5. Place in order the 4 steps of the cross-bridge cycle beginning immediately after tropomyson shifts to reveal the binding sites.
    a. Attachment of the cross-bride to a thin filament
    b. Re-energizing the cross-bridge by hydrolysis of ATP
    c. Movement of the cross-bridge, producing tension in the thin filament and dissociation of the ADP and Pi from the crossbridge
    d. Detachment of the cross-bridge from the thin filament
    • a. Attachment of the cross-bride to a thin filament
    • c. Movement of the cross-bridge, producing tension in the thin filament and dissociation of the ADP and Pi from the crossbridge
    • d. Detachment of the cross-bridge from the thin filament
    • b. Re-energizing the cross-bridge by hydrolysis of ATP
  6. Which portion of the myosin molecule forms the long tail that joins with other myosin molecules to form the backbone of the thick filament?
    Heavy chains
  7. Place the events involed in skeletal muscle activation and contraction into the correct order.
    a. Tropomyson moves, exposing cross-bridge binding sites on actin
    b Cross-bridges bind to actin
    c. Myosin heads bind ATP and detach from actin
    d. Ca2+ binds to troponin
    e. Ca2+ is releases from the sarcoplasmic reticulum (SR)
    f. Cross-bridges undergo a rotation, or power stroke
    • e. Ca2+ is releases from the sarcoplasmic reticulum (SR)
    • d. Ca2+ binds to troponin
    • a. Tropomyson moves, exposing cross-bridge binding sites on actin
    • b Cross-bridges bind to actin
    • f. Cross-bridges undergo a rotation, or power stroke
    • c. Myosin heads bind ATP and detach from actin
  8. Which of the following occur during concentric contraction?
    a. The H zone gets smaller
    b. The A band gets smaller
    c. THe thin filament shortens
    d. THe I band gets smaller
    • a. The H zone gets smaller
    • d. THe I band gets smaller
  9. The transverse tubules or T-tubules:
    • Conduct action potentials
    • Are formed from the plasma membrane
  10. Excitation-contraction coupling pairs:
    the generation of an action potential with the release of calcium to begin contraction
  11. The action of the Ca2+ ATPase pumps:
    moves calcium into the SR, against its gradient, and allows fibers to relax
  12. During the power stroke step of the cross-bridge cycle :
    ADP and Pi are released from the cross-bridge head.
  13. Which of the following are examples of isotonic contractions:
    a) an active frog muscle in lab undergoing lengthening where the force generated by the muscle is held constant
    b) AN active frog muscle in lab undergoing shortening where the velocity generated by the muscle is held constant
    c) An active frog muscle in lab undergoing shortening where the force generated by the muscle is held constant
    a,c
  14. What is the motor end plate?
    A specialized part of the sarcolemma near the neuromuscular junction
  15. The general term for the activation of the force-generating sites within muscle fibers, the cross-bridges, is called a(n) _____
    contraction
  16. The myosin molecule is composed of 2 larger ____chains and 4 smaller ____chains.
    heavy, light
  17. WIth reference to muscle physiology, which best defines the term "contraction."
    Activation of cross-bridge cycling
  18. A band
    Made of thick filament, appearing dark
  19. I band
    Are the portions of thin filament that do not overlap the thick filament
  20. H Zone
    Narrow light band in the center of the A band, it corresponds to the opposing ends if 2 sets of thin filaments in each sarcomere
  21. Z lines
    One end of each thin filament is connected to a network of interconnecting proteins known as the Z line (The other ends overlaps the thick filament)
  22. M line
    A narrow dark band in the center of the H zone(Proteins that link together th ecentral region of adjacent thick filaments)

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