In clinical study design; Compare and contrast the concepts of:
-Internal and external validity
-Bias
-Confounding
Ditto
-What are the potential sources of bias in clinical trials?
-Which strategies to eliminate or control for bias?
Ditto
Outline the hierarchy of evidence generated by various study designs??
Ditto
Compare and contrastÂ the advantages & disadvantages of various study designs: Prospective
Retrospective
Case-control
Cohort
Cross-sectional
Randomized controlled clinical trials
Systematic review
Meta-analysis
Ditto
Delineate the difference between:
Parallel & crossover study designs.
Ditto
Select from various biostatistical measures to appropriately compare groups or their assessmentsfrom various study designs and use their findings/output to interpret results
Ditto
The different Test eg Chi square ANOVA etc
Define and evaluate odds, odds ratio, risk/incidence rate, risk ratio/relative risks (RRs), and other risk estimates. Compute and evaluate number neededto treat and number needed to harm. Define andcalculate terms such as point and period prevalence,incidence rate, prevalence rate, absolute risk difference, and RR difference
Ditto
Define and calculate terms such as:
-True positive
-False positive
-True negative
-False negative
-Sensitivity
-Specificity
-Positive predictive value
-Negative predictive value
-Positive likelihood ratio and
-Negative likelihood ratio