Magnesium Sulfate

Card Set Information

Author:
Lhernandez
ID:
294548
Filename:
Magnesium Sulfate
Updated:
2015-02-01 18:26:06
Tags:
LVAPEC PharmacologyGroup9
Folders:
Drug Profiles,Pharmacology Group 9
Description:
Magnesium Sulfate
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  1. Magnesium Sulfate Class
    Electrolyte
  2. Magnesium Sulfate MOA
    • Reduces striated muscle contractions and blocks peripheral neuromuscular transmissions by reducing acetylcholine release at the myoneural junction
    • Manages seizures in toxemia of pregnancy
    • Induces uterine relaxation
    • Can cause bronchodilation after Beta-agonist and anticholinergic have been used.
  3. Magnesium Sulfate Indications
    • Eclamptic Seizure
    • Torsades
    • Hypomagnesaemia
  4. Magnesium Sulfate Contraindications
    • Heart Blocks
    • Myocardial Damage
    • Shock
  5. Magnesium Sulfate Adverse Reactions
    • CNS depression
    • Circulatory collapse
    • Facial flushing
    • Diaphoresis
    • Hypotension
    • Decreases reflexes
  6. Magnesium Sulfate Dosage
    • Adult:
    • Seizure activity associated with pregnancy: 1-4g IV/IO over 3 mins max dose 30-40g/day

    Torsades/Cardiac arrest due to hypomagnesaemia:  1-2g in D5W IV/IO over 5-20mins

    Asthma: 1-2g mixed in 50-100mL over 10-20mins

    • Peds: IV/IO infusion 25-50mg/kg over 10-20mins(faster if treating Torsades)
    • Asthma: 25-50mg/kg over 10-20mins

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