1. Hypo releases CRH to stimulate pit
2. Pit simulated releases ACTH
3. ACTH stimulus estrogens/androgens.
- 4. Estrogens and androgens stimulate skeletal system, integument, brain
- *stimulates small amounts of and or and estro for essential purposes in opposite sex like sex drive
5. If estrog and Andre levels high, then they will inhibit ACTH and crh