- Side effects: CNS: tingling sensation, fainting
- Skin: sensation of heat waves (peripheral vasodilation), pain, burning at IV site, necrosis and sloughing
- CV: hypotension, bradycardia, cardiac dysrhythmias, cardiac arrest, severe venous thrombosis
Give 0.5 to 1.0 mL/min or slower to avoid cllulitis, necrosis and sloughing at IV site
Use small bore needle in larg vein to minimize venous irritation and undesirable reactions
BP may fall after IV injection so monitor BP, EKG, flow rate and watch pt closely
Flush IV line prior to and immediately following administration of such drugs as sodium bicarb, or other catecholamines to avoid precipitate.