Bayesian Probability
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Important facts to remember for Bayesian analysis: XL lethal disease
In X linked lethal diseases,
those who are affected don't go on to reproduce.
In the absence of fam hx...
...the prior probability of the
mother
(of an affected child)
being a carrier is 2/3.
...the prior probability of the
mother being a non carrier is 1/3.
This would mean the disease is de novo.
...the prior probability of the
grandmother
(of an affected child)
being a carrier is 1/3.
...the prior probability of the
aunt
of an affected child,
being a carrier is 1/6.
Important facts to remember for Bayesian analysis: AR disorders
An unaffected sibling of someone who is affected with an AR trait, has a 2/3 chance of being a carrier.
Important facts to remember for Bayesian analysis: Determining Zigocity
70% of twins are dizygotic
30% of twins are monozygotic
Important facts to remember for Bayesian analysis: Determining paternity
You must assume that paternity/nonpaternity are equally likely (50/50).
Card Set Information
Author:
mlbcasey
ID:
295531
Filename:
Bayesian Probability
Updated:
2015-02-11 00:01:40
Tags:
Bayesian
Folders:
Description:
Bayesian analysis
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