Bayesian Probability

Card Set Information

Author:
mlbcasey
ID:
295531
Filename:
Bayesian Probability
Updated:
2015-02-10 19:01:40
Tags:
Bayesian
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Description:
Bayesian analysis
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  1. Important facts to remember for Bayesian analysis:  XL lethal disease
    In X linked lethal diseases, those who are affected don't go on to reproduce.

    In the absence of fam hx...

    ...the prior probability of the mother (of an affected child) being a carrier is 2/3.

    ...the prior probability of the mother being a non carrier is 1/3.  This would mean the disease is de novo.

    ...the prior probability of the grandmother (of an affected child) being a carrier is 1/3.

    ...the prior probability of the aunt of an affected child, being a carrier is 1/6. 

  2. Important facts to remember for Bayesian analysis:  AR disorders
    An unaffected sibling of someone who is affected with an AR trait, has a 2/3 chance of being a carrier.
  3. Important facts to remember for Bayesian analysis:  Determining Zigocity
    70% of twins are dizygotic

    30% of twins are monozygotic
  4. Important facts to remember for Bayesian analysis:  Determining paternity
    You must assume that paternity/nonpaternity are equally likely (50/50).

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