Hemoglobin.txt

Card Set Information

Author:
rmslim1
ID:
295989
Filename:
Hemoglobin.txt
Updated:
2015-02-16 10:57:16
Tags:
Hematology
Folders:

Description:
Hemoglobin
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    • author "rmslim1"
    • tags "Hematology"
    • folders ""
    • description ""
    • fileName "Hemoglobin"
    • Adult hgb A
    • Has 4 heme groups & 4 polypeptide chains (2 alpha & 2 beta)
  1. Function of hgb
    Carry O2/CO2 to/from tissues
  2. Heme's Oxygen affinity regulated by
    2,3 DPG
  3. P50 value =
    26.52 mm/hg
  4. >O2 affinity &
    To the left
  5. DPG O2 curve shifts
    To the right
  6. What is Transferin
    Heme messenger
  7. Hgb breakdown @ birth
    HGB F 60-80% / hgb A 20-40%
  8. Hgb breakdown for adults
    HGB A 95-97% / HGB A2 2-3% / HGB F 1%
  9. HGB affinity for CO
    210x more affinity than oxygen
  10. Fe2+ (ferrous state) is oxidized to
    F3+ (ferric state)
  11. RBC lifespan (in days)
    Adult 120 / fetus 60-70 / premie 30-50

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