Card Set Information
Genes associated with neural tube defects
Gap junction alpha 1, 5
Glutamate receptor interacting protein 1
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A, adhesion
Growht arrest and DNA damage inducible - cell cycle
Nucleosome assembly protein
Sodium-dependent lysophosphatidylcholine symporter 1, blood brain barrier, LPC
Phosphatase and actin regulator, regs PP1, NT and optic fisure, integrin sigaling
Cell cycle checkpoint control protein RAD9B
Tellurium resistance protein, possible barrier function?
Hamartin? Inhibits growht factor simulation, mTorc1 something, tubor supressor, MT transport?
Tuberin, growth factor response inhibition, GAP for RheB, activator of mTORC1, MT transport, something with Rab
DNA repair protein XRCC2, homologous recombination, holiday junctions
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
Makes LPA, motility related processes, migration
Plexin B, SEMA signaling, Rho A activation downstream, Brain development, actin cytoskeleton. Rac1 and CDC42 might work also. Down regulates macrophage migration in wound healing.
Ligand to plexin
Activating molecule in BECN1-regulated autophagy protein 1
Autophagy in ner vous sytem, proliferation, survival
Apoptotic protease-activating factor 1
Two different mutations causing NTDs