Therapeutics - ADHD 1

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Author:
kyleannkelsey
ID:
296502
Filename:
Therapeutics - ADHD 1
Updated:
2015-02-22 14:00:53
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Therapeutics ADHD
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Therapeutics - ADHD
Description:
Therapeutics - ADHD
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  1. What are the general DSM-IV diagnostic criteria for ADHD?
    • Symptoms present:
    • > or = to 6 months
    • > or = to 2 settings
    • Several symptoms before 12 years
    • Clear school or work performance impairment
  2. What are the diagnostic symptoms of Inattention ADHD?
    • > or = to 6 symptoms up to 16 yoa
    • > or = to 5 symptoms at >17 yoa
    • Symptoms:
    • Careless mistakes or failure to give detail
    • Trouble holding attention
    • Not listening
    • Failure to finish activities or take direction
    • Avoids mental effort
    • Looses things
    • Forgetful
    • Easily distracted
  3. What are the diagnostic symptoms of Hyperactivity ADHD?
    • > or = to 6 symptoms up to 16 yoa
    • > or = to 5 symptoms at >17 yoa
    • Symptoms:
    • Fidgets
    • Leaves seat when expected to remain
    • Runs about or climbs
    • Does not take part in leisure activaties
    • On the go
    • Talks excessively
    • Blurts answer before question is complete
    • Trouble waiting turn
    • Interrupts
  4. What are the S/S of adult ADHD?
    • Poor organization
    • Procrastinate
    • Chronically late
    • Frequently losing things
    • Interrupt others
    • Blurt out inappropriate thoughts
    • Easily flustered
    • Hypersensitive to criticism
    • Explosive temper
  5. What are the treatment modalities for ADHD?
    • Pharmacotherapy
    • Psychosocial
    • Behavior modification
    • Parent training
    • Social skills training
  6. What were the best treatment groups for ADHD in the MTA study?
    • Single medication
    • Combination Therapy
  7. Why are stimulant doses different for each patient?
    Highly variable absorption
  8. What is the efficacy of Stimulants in the treatment of ADHD?
    60-70%
  9. What is the brand name for Methylphenidate?
    Ritalin®, Metadate®, Methylin®, Concerta®, Quillivant XR™
  10. What is the generic name for Ritalin®?
    Methylphenidate
  11. What is the generic name for Metadate®?
    Methylphenidate
  12. What is the generic name for Methylin®?
    Methylphenidate
  13. What is the generic name for Concerta®?
    Methylphenidate
  14. What is the generic name for Quillivant XR™?
    Methylphenidate
  15. What is the brand name for Dexmethylphenidate
    Focalin®
  16. What is the generic name for Focalin®?
    Dexmethylphenidate
  17. What is the brand name for Mixed amphetamine salts?
    Adderall®
  18. What is the generic name for Adderall?
    Mixed amphetamine salts
  19. What is the brand name for Dextroamphetamine
    Dexedrine®
  20. What is the generic name for Dexedrine?
    Dexedrine
  21. What is the brand name for Lisdexamfetamine
    Vyvanse®
  22. What is the generic name for Vyvanse ?
    Lisdexamfetamine
  23. What is the brand name for Methamphetamine
    Desoxyn®
  24. What is the generic name for Desoxyn?
    Methamphetamine
  25. What are the stimulants for ADHD?
    • Methylphenidate (Ritalin®, Metadate®, Methylin®, Concerta®, Quillivant XR™)
    • Dexmethylphenidate (Focalin®)
    • Mixed amphetamine salts (Adderall®)
    • Dextroamphetamine (Dexedrine®)
    • Lisdexamfetamine (Vyvanse®)
    • Methamphetamine (Desoxyn®)
  26. What are the immediate release stimulant products for ADHD?
    Ritalin®, Adderall®, Desoxyn®
  27. What is the DOA of Ritalin®, Adderall®, Desoxyn®?
    3-4 hours duration, possibly up to 12 hours with Adderall®
  28. What are the immediate acting Stimulant agents (Ritalin®, Adderall®, Desoxyn®) useful for?
    Useful for dose titration in smaller children
  29. What is the dosing interval for IR stimulant formulations (Ritalin®, Adderall®, Desoxyn®)?
    BID – TID dosing
  30. What are the cons for IR stimulants?
    • Rebound
    • Embarrassment – kids don’t want to go to nurse’s station to get their med 2-3x a day
  31. What drug is the R-isomer of methylphenidate?
    Dexmethylphenidate (Focalin®)
  32. What are the benefits of Dexmethylphenidate (Focalin®)?
    • “Smoother” effect
    • Less insomnia
    • Less rebound
    • Fewer “ups and downs”
    • May allow for higher doses
  33. When initiating therapy with Dexmethylphenidate (Focalin®), how should you dose the patient?
    Start at half usual methylphenidate dose
  34. What are the pros of ER Stimulant formations?
    • QD dosing
    • Increased compliance

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