Anti-malarials

Card Set Information

Author:
trincam2008
ID:
296560
Filename:
Anti-malarials
Updated:
2015-02-22 20:31:26
Tags:
antimalarials psa
Folders:
PSA,infection
Description:
Anti-malarials prophylaxis, treatment, s.e, when 23/2/15
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  1. Prophylaxis
    1. High risk of P.falciparum
    2. Low risk
    (Plasmodium falciparum)
    • 1. mefloquine, doxycycline, Malarone (atovaquone + proguanil)
    • (high risk: mountain M - mefloquine, malarone, doxy mạnh)

    • 2. chloroquine, proguanil
    • (low risk: chloro vừa đủ thành pro)
  2. Treatment of active infection
    Always depend on species, if unknown treat for P.falciparum

    • (giữ lại 1 cái từ prophylaxis)
    • 1. P. falciparum: quinine + tetracycline
    • (thưởng xuyên: tetra 4 đầu muỗi quy niên)
    • 2. Non - P.falciparum: chloroquine + primaquine
    • (giữ lại chloro + (trước là pro, chừ là đỉnh, hoa hậu) prima-quine
  3. Prophylaxis: Side effects + when to take
    • 1.
    • - Mefloquine
    • +psychiatric reaction (mê flo độc -> psy)
    • +long t1/2 so 2-3 weeks b4 travel and 4 weeks after leaving

    • - Malarone:
    • +mild gastric problems
    • + good for short trip (one ngắn)2 days before and 7 days after)

    • 2.
    • - Chloroquine
    • + Visual change, seizures
    • + 1 weeks b4 and 4 after

    (thuong 4 week after)
  4. Rx + se
    • 1.
    • Quinine
    • - tinnitus

    • 2.
    • Primaquine
    • - mild gastric symptoms
    • - not in G6PD deficiency - haemolysis
    • Both: primaquine & chloroquine: caution in G6PD dè

    (quy nieen - nghe văng vẳng, hoa hậu - đau bụng, đi GP G6PD)
  5. Riamet - artermether + lumefantrine
    • Falciprum
    • S.E: ↑ QT, abdo pain, GI upset
    • CI: Hx of arrythmias, ↑QT

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