Therapeutics - Addictions 1

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  1. Personality disorders have what essential feature?
    Pattern of inner experience and behavior that deviates markedly from the expectation of the individual’s culture.
  2. Personality disorders manifest in what ways?
    • Cognition (ways of perceiving and interpreting self, other people and events)
    • Affectivity (the range, intensity
    • Lability and appropriateness of emotional response)
    • Interpersonal functioning or impulse control
  3. What is a Substance?
    Psychoactive agent having the potential to cause dependence or abuse
  4. What is Addiction?
    “substance use dependence” – use this term instead of addiction
  5. What is a Dependence?
    Physical, psychological or both
  6. What is a Substance Use Disorders?
    Defined by DSM-IV-TR
  7. What is a Substance?
    Induced Disorder
  8. What are the features of Alcohol and Sedative-Hypnotic intoxication?
    Psychomotor impairment, exaggerated emotional response, impaired judgment, ataxia, slurred speech, decreased concentration, respiratory depression and death
  9. What are the features of Cocaine, Amphetamine and other stimulants intoxication?
    Irritability, dilated pupils, increased blood pressure, panic reactions, paranoid psychosis, flight of ideas, feelings of grandiosity, stereotypy (repetitive seemingly meaningless behavior), hyperthermia, seizures, respiratory depression, acute heart failure, stroke, and death.
  10. What are the features of Opioids?
    Constipation, constricted pupils, decreased sensations of pain, decreased concentration, respiratory depression, comma, and death.
  11. What is Withdrawal?
    • Reactions reflecting the unmasking of compensatory adaptive biological changes that have occurred after chronic drug ingestion.
    • Manifest as the opposite of the acute effects of the drug (but not always).
  12. What are the objectives to treat in withdrawal?
    Prevent severe complications, i.e. seizures for some drugs, supportive, and reduce symptomatology
  13. What medical conditions arise from use of Alcohol?
    Liver, esophageal varices, Wernicke’s, Korsakoff’s dementia, sleep disorders, stroke, cardiac diseases, cancer, and others
  14. What medical conditions arise from use of Amphetamine?
    Sleep disorders, poor nutrition, hypertension, and arrhythmias
  15. What medical conditions arise from use of Cocaine?
    Sleep disorders, eating disorders, sexual dysfunction, hypertension, arrhythmias, and nasal septum perforation, taste and smell decreased
  16. What medical conditions arise from use of Opiates?
    Constipation and sexual dysfunction
  17. What medical conditions arise from use of Tobacco?
    Cardiovascular disease, cancer, and chronic lung disease
  18. What are the CNS Depressants?
    • Opioids – morphine, heroin, methadone
    • Alcohol
    • Gamma hydroxybutyrate
    • Sedative-hypnotics – benzodiazepines, barbiturates
    • Inhalants – gasoline, toluene
  19. What are the CNS Stimulants?
    • Amphetamines – dextroamphetamine, methamphetamine
    • Methylphenidate
    • Cocaine
    • MDA, MDMA (Ecstasy)
    • Nicotine
    • Caffeine
  20. What are the Hallucinogens?
    • LSD
    • Mescaline
    • Cannabis
    • PCP
  21. What are the Uppers?
    Caffeine, Nicotine, Amphetamines, Cocaine
  22. What are the Downers?
    Alcohol, benzodiazepines, barbiturates, opiates, muscle relaxants, sleeping pills
  23. What are the All Arounders?
    Cannabis, Psilocybin, LSD, Ecstasy, Mescaline, PCP, cough syrup, some sleeping pills
  24. Oral takes how long to reach the desired effect?
    Time to peak 30-60min = slow
  25. Mucous membrane (nasal, i.e. snorting cocaine etc.) takes how long to reach the desired effect?
    Time to peak 1-2min
  26. What are the risks of IV?
    Overdose, infection
  27. What is the risk of SQ?
  28. Time to peak for Inhaling:
    7-10 seconds
  29. Time to peak for Intravenous:
    15-30 seconds
  30. Time to peak for Intramuscular:
    3-5 minutes
  31. Time to peak for Subcutaneous:
    3-5 minutes
  32. Time to peak for Snorting or Mucosal Exposure:
    3-5 minutes
  33. Time to peak for Oral:
    20-30 minutes
  34. Time to peak for Transdermal:
    varies, patches 6 hrs+ until peak
  35. What are the therapeutic goals of treating substance use?
    • Abstinence
    • Harm reduction
Card Set:
Therapeutics - Addictions 1
2015-02-23 16:26:41
Therapeutics Addictions
Therapeutics - Addictions
Therapeutics - Addictions
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