COPD

Card Set Information

Author:
traceyj30
ID:
296966
Filename:
COPD
Updated:
2015-02-26 19:23:57
Tags:
Issue COPD
Folders:
Patho
Description:
Chronic Bronchitis and Emphysema
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  1. ABG'S in Chronic Bronchitis
    • Elevated PaCo2
    • Decreased PO2
  2. Treatments of Chronic Bronchitis
    • Inhaled Short-acting B2 agonists
    • Inhaled anticholinergic bronchodilators
    • Cough suppressants
    • oral/inhaled corticosteroids
    • Theophylline products
    • low dose O2 therapy for patients with PaO2 lower than 55mmHG
  3. Causes of Chronic Bronchitis
    • Smoking 90%
    • Repeated airway infection
    • Genetic predisposition
    • Inhalation of physical or chemical irritants
  4. Chronic Bronchitis Pathogenesis
    How does the disease progress
    • Chronic inflammation and swelling of the bronchial mucosa results in scarring
    • ¬†Elevated IL 8 levels recruit neutrophil activation
    • Elevated CD 8 T Lymphocytes
    • extends into surrounding alveoli
    • prevents proper oxygenation and can obstruct airway
  5. Chronic bronchitis pathogenesis con't
    • Hyperplasia of bronchial mucous gland and goblet cells
    • increased mucus production
    • can form mucous plug¬†
    • airway gets thinner
  6. Increased Bronchial wall thickness in Chronic Bronchitis
    • resistance increase work of breathing
    • increased O2 demands
    • ventilation-perfusion mismatch
    • High CO2 retention
    • increase pulmonary artery resistance
  7. Chronic Bronchitis: Clinical manifestations
    • SOB on exertion
    • excessive sputum
    • chronic cough
    • excess body fluids edema
    • cyanosis
    • "Blue Bloaters"
  8. Chronic Bronchitis: Diagnosis
    • CXR
    • Increased vascular markings
    • congested lung fields
    • enlarged horizontal cardiac silhouette
    • evidence of previous infection

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