ace inhibitor

Card Set Information

Author:
klerandi
ID:
297153
Filename:
ace inhibitor
Updated:
2015-03-01 02:41:04
Tags:
lf
Folders:
renin
Description:
xlvn
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  1. designed with a carboxyl group on a proline and a thiol group
    captopril BN2
  2. lysine derivative of enalaprilat
    lisinopril
  3. treatment of mild-moderate HTN
    ace inhibitor prodrug
  4. long acting ACE in hibitor

    requires activation by hydrolysis of its ethyl ester to form diacid enalaprilat
    enalapril maleate BN
  5. metabolized to the active diacid benazaprilat
    benazepril HCl (BN)
  6. forms the diacid quinaprilate in the body

    more potent than Captopril and equipotent form of Enalapril
    quinapril HCl (BN)
  7. faster than enalapril
    ramipril
  8. suppresses ACE activity for up to 12 hrs with 80% inhibition of the enzyme still observes after 24 hrs
    ramiprilat
  9. phosphorous containing ACE inhibitor
    fosinopril sodium
  10. indole containing ACE inhibitor
    trandolapril
  11. 1. enalapril
    2. benazepril
    3. quinapril
    4. ramipril
    5. fosinopril
    6. trandolapril
    • 1. enalaprilat
    • 2. benazaprilat
    • 3. quinaprilate
    • 4. ramiprilat
    • 5. fosinoprilat
    • 6. trandolaprilate

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