HIV

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Author:
rafiki121
ID:
297247
Filename:
HIV
Updated:
2015-03-01 23:44:19
Tags:
HIV
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Description:
Nu 202
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  1. PCP
    Happens in the lungs.  Presence of candidiasis increases risk of PCP

    • Fever
    • Dry cough
    • Chest tightness
    • SOB

    • TMP/SMX
    • Pentamidine second line therapy when TMP/SMX can't be taken.
  2. Candidiasis
    • Oral or vaginal
    • T-cell count < 200

    • Mouth, throat - burning pain
    • Altered taste
    • Difficulty swallowing
    • White or pinkish red blotches
    • Vaginal- thick white discharge
    • Burning
    • Itching
    • Rash
    • Tenderness

    • Antifungals
    • Vaginal cream
  3. Mycobacterium TB (MTB)
    Respiratory system. Airborne spread

    • Fever
    • Chills
    • Cough
    • Weight loss
    • Night sweats
    • Fatigue
    • Lymphadenopathy

    • Latent TB:
    • Isoniazid
    • Rifampin

    • Active TB:
    • Isoniazid
    • Rifampin
    • Pyrazinamide
    • Ethambutol
    • Streptomycin
  4. Mycobacterium Avium Complex (MAC)
    • GI, Respiratory, CNS.  Ingestion or inhalation. Found in foods, water, soil and animals.
    • CD4 count <50 cells/uL

    • Fever
    • Chills
    • Weight loss
    • Night sweats
    • Fatigue
    • Muscle wasting
    • Abdominal pain
    • Can cause enlargement of liver, spleen as well as lymph nodes

    • Clarithromycin
    • Azithromycin
    • Ethambutol
    • With or without rifabutin

    • When CD4 <50
    • Clarithromycin and azithromycin
  5. Toxoplasma Gondii
    Usually affects the CNS.  Common source is bird droppings or cat feces.  Undercooked meat, especially pork, lamb or venison.

    • Headache
    • Fever
    • Confusion
    • Impaired coordination
    • Can progress to seizure

    Once contracted, lifetime suppressive treatment like PCP TMP/SMX
  6. Cryptosporidiosis
    • GI system. Symptoms worse with CD4 <200
    • Spread by feces of infected humans or animals. Food or water contaminated with animal feces.

    • May experience prolonged & severe bouts of diarrhea & malabsorption that can be difficult to treat. 
    • Watery diarrhea primary symptom
    • Abdominal pain
    • N/V
    • Weight loss
    • Loss of appetite
    • Dehydration
    • Flatulence
  7. Cytomegalovirus (CMV)
    • CMV retinitis
    • Most common with CD4 <100
    • Spread via contact with saliva, cervical secretions, urine, semen, breast milk and feces.

    • Cannot be cured, can only be stopped from causing diseases.
    • tx: Ganciclovir (Cytovene)
  8. Herpes Simplex, Zoster
    • Skin/ mucous membrane: Cold sores, shingles
    • Spread by contact or exacerbated in weakened conditions

    Antivirals: Valtrex

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