Membranoproliferative glomerulonephritis (MPGN) is a _____________HS, in which immune complexes are deposited in the _____________ on the __________ side of the basement membrane. These complexes stimulate ____________________.
generalized Type III; glomerular vessels; endothelial; mesangial cell and endothelial proliferation
With MPGN, increased _______ and _______ induce mesangial and endothelial proliferation and fibrosis.
Comparative mycobacterial testing in cattle makes use of a ______________ HS response.
False negatives can be seen on a comparative mycobacterium test in cattle if... (4)
infection is in early stages, advanced disease, recent post-partum, and very old animals
False positive can be seen on comparative mycobacterium test in cattle if... (1)
the animal is infected with other types of mycobacterium.
With short thermal testing for mycobacterium in cattle, you inject ______________ and examine the animal's ________ 4-8 hours later.
a large volume of tuberculin solution SQ; temperature
With the stertmont test, you administer ________ of tuberculin at the ________, 7 days apart.
2 doses; same site
You can test for mycobacterium by stimulating lymphocytes in vitro with mycobacterial Ag and then measuring the production of ______.
Tubercle formation occurs with ________ HS and results in _____________; it can be caused by... (3)
Type IV; granuloma/granulomatous inflammation; tuberculosis, brucellosis, certain fungi
Allergic contact dermatitis occurs with __________ HS; it is induced by ________ to chemicals, or other Ag and _________ bind the Ag directly to stimulate a _______ immune response and _______ production.
type IV; topical exposure; langerhans cells; Th1; IFNγ
With allergic contact dermatitis, once IFNγ production is stimulated, _______ and ________ migrate to the epidermis and attack sensitized epidermal cells to create ________.
CTLs; NKT cells; cutaneous vesicles
Atopic dermatitis (Type I HS) presents as... (3)
In contrast, allergic contact dermatitis (Type IV HS) presents as... (4)