PHRD6925 MedChem Lecture 4 - Drugs affecting serotonin receptors and serotonergic neurotransmission

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Author:
daynuhmay
ID:
297630
Filename:
PHRD6925 MedChem Lecture 4 - Drugs affecting serotonin receptors and serotonergic neurotransmission
Updated:
2015-03-05 01:49:30
Tags:
medchem
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medchem
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  1. identify:
    serotonin
  2. what functional group is this?
    indole
  3. which portion of this 5-HT1A receptor agonist determines specificity within the receptor?
    arylpiperazine
  4. which portion of the 5-HT1A receptor agonist helps with bioavailability?
    terminus
  5. identify:
    5-HT1A antagonists
  6. identify:
    • 5-HT1D receptor agonists
    • (retain serotonin's indole ring structure)
    • (sumatriptan, zolmitriptan)
  7. therapeutic use for 5-HT1D agonists
    migraine (triptans)
  8. identify:
    • 5-HT1F agonists
    • (indole adjacent to amine)
  9. identify:
    5-HT2A receptor agonists
  10. identify:
    5-HT2A receptor antagonists

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