Pharmaceutics II (Exam II) Modified/Sustained Release Dosage Forms and Drug Delivery Systems
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What are the two main aspects of drug delivery?
Spatial placement: relates to targeting of drug to a specific organ or tissue
temporal delivery: refers to controlling the rate of delivery to target tissue
What is drug blood level?
concentration of drug in blood or plasma
Why does intravenous or
extravascular route (orally, rectally, etc) doses not maintain the drug blood
level within the therapeutic range for extended periods of time?
Inability of conventional dosage forms to control temporal delivery
How does a conventional drug therapy perform?
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