2.4 Vitamin C

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Author:
efrain12
ID:
298362
Filename:
2.4 Vitamin C
Updated:
2015-03-13 23:01:01
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Description:
Vit C
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  1. Symptoms of scurvy and biochem reasons why a deficiency of vita c causes these symptoms) scurvy symptoms (3)
    -retarded wound healing

    -bleeding gums

    -capillary ruptures
  2. Symptoms of scurvy and biochem reasons why a deficiency of vita c causes these symptoms)
    Vit C deficiency leads to scurvy bc it is essential to collagen crosslinking steps in collagen synthesis
  3. Main sources of vit c (5)
    -asparagus

    papaya

    oranges


    cantaloupe


    Cauliflower
  4. How does body regulate the absorption of vita c and what are some reasons to avoid high levels of vita c intake ) (1+2)
    Body regulates absorption by increasing/decreasing SVCT 1 receptors in respospnse to vita c levels

    • -high intake= absorption 16%
    • -Low intake= absorption is 98%
  5. How does body regulate the absorption of vita c and what are some reasons to avoid high levels of vita c intake )
    Vitamin c can be excreted in urine either intact or as dehydroascorbic acid. Dehydroascorbic acid yields numerous compounds including oxalic acid which has been shown to be implicated in kidney stones. Also high intakes lead to GI distress
  6. RDA for vita c (2)
    90 mg/day for females

    75 mg/day for males
  7. TUL vita c
    2000 mg/day or else GI distress can occur
  8. Be able to describe vitamin c contribution to hydroxylation reactions )
    Vitamin c as ascorbic acid assist in hydroxylation reactions (adding OH group) by regenerating the minerals redox state

    Ex) Fe3 -> Fe2
  9. Functions of vitamin c) (5)
    -collagen synthesis

    -carnitine synthesis

    -NT synthesis

    -antioxidant activity

    -pro-oxidant activity
  10. Be able to describe the role of antioxidants and free radicals in detail)
    • Free radicals are atoms with an unpaired electron so they steal electrons from other balanced cell causing tissue damage and sometimes DNA damage.
    • *can be formed by almost anything including natural processes
  11. Be able to describe the role of antioxidants and free radicals in detail) (2)(
    Antioxidants like vitamin c neutralize free radicals by donating an electron to their outer shell

    • Some destroy the free radicals
    • *usually minerals
  12. Literature of vitamin c and various health conditions ) vita c and common cold
    -it does not appear to prevent or reduce the cold significantly only a very modest amount like 3-13%.
  13. Literature of vitamin c and various health conditions ) vita c and caner (3)
    -it does not have protective effects against cancer

    -some studies show minor risk reduction in certain cancers though

    -for sure fruits and veggies have shown to have a protective effect against cancer
  14. Literature of vitamin c and various health conditions ) vita c and cvd (1+2)
    Does decreased risk but intake has to be from foods and not supplements because...

    -vita c though to decrease oxidation factor of cholesterol & reduce monocyte adherence

    -vita c thought to help by facilitating new collage formation in vascular endothelial cells
  15. Discuss the relationship between vita c and iron absorption)
    Fe2 is easier to absorb than Fe3 so vita c enhances absorption bc it reduces iron to Fe2

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