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Variation in size of erythrocytes?
Lymphocyte that occurs in response to viral infection and that is common in infectious mononucleosis; Reactive lymphocyte ?
a determination of the relative numbers of each type of white blood cell when a specified number (usually 100) is counted; white blood cell differential count; leukocyte differential count
having reduced color or hemoglobin content
having a larger-than-normal cell size
having a smaller-than-normal cell size
having normal color
having a normal cell size
the engulfing of a foreign particle or cell by another cell
significant variation in the shape of red blood cells
see atypical lymphocyte
What is the purpose of a WBC differential count?
- determine the percentage of each type of WBC in peripheral blood smear
- make observations on RBC morphology
- estimate platelet number
Describe the area of the smear in which the differential count should be performed.
area near the feathered edge of the smear where RBC are barely touching each other.
What three characteristics of WBCs are evaluated in cell identification?
- Cell size
- Nucleus: shape and structure
- Cytoplasm: amount, color, inclusions
what is the percentage of segmented neutrophils?
- 1m/o: 15-35
- 6 and 12 y.o.: 45-50
- adult: 50-65
what is the percentage of band neutrophils?
- 1m.o: 7-13
- 6 y.o and Adult: 0-7
- 12 y.o.: 6-8
what is the percentage of Eosinophils?
1m/o; 6y.o.; 12 y.o.; and adult: 1-3
what is the percentage of Basophils?
1m/o; 6y.o.; 12 y.o.; and adult: 0-1
- 1m/o: 5-8
- 6y.o.: 4-8
- 12 y.o: 3-8
- adult: 3-9
- 12 y.o.: 35-40
- adult: 25-40
What are the functions of neutrophils?
- active in phagocytosis
- increased during bacterial infections
What are the functions of monocytes?
primary defense against invading pathogenic organisms
What are the functions of lymphocytes?
- important in antibody production
- communicating with other cells in immune system
- production of cytokines.
conditions that affect WBC percentage?
- Bacterial infection
- Viral infection
- infectious mononucleosis
- parasitic infection
- allergic reactions
Increased total WBCs, increased percentage of neutrophils andbands
Decreased WBCs, increased percentage of lymphocytes
Increased total WBCs,
increased atypical lymphocytes
- parasitic infections
- allergic reaction
Total WBCs usually increased
increase in type of leukocyte involved
RBC morphology during Iron deficiency anemia,thalassemias
RBC morphology in case of Vitamin B12 deficiency, folate deficiency?
RBC cell morphology in case of Hereditary spherocytosis
RBC hemoglobin content in case of Iron deficiency anemia and Spherocytosis is