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remnants of RNA and other basophilic nuclear material remaining inside the red blood cell after the nucleus is lost from the cell; small purple granules in red blood cells stained with Wright’s stain
elongated, cigar-shaped red blood cell
an immature blood cell normally found only in the bone marrow
the appearance of an increased number of immature neutrophil forms in the peripheral blood
shift to the left
List three conditions in which abnormal RBC morphology can be found?
- Iron deficiency anemia
- Folic Acid deficiency
- Vitamin B12 deficiency
- sickle cell disease
How can RBC indices be used to classify anemias?
List three conditions in which abnormal WBC morphology can be found?
characteristic of chronic leukemias?
Chronic: worsen slowly total number of abnormal WBC small. abnormal cells still function to some extent. Bone marrow not affected to large degree.
List cause of thrombocytosis ?
- elevated platelet do to:
- reaction to inflammatory condition
- secondary to other blood disorders
- removal of the spleen
characteristic of acute leukemia?
- worsen rapidly
- abnormal immature cells that cannot carry out normal immune function.
List cause of thrombocytopenia.
- decreased platelet count do to:
- radiation exposure
- some drugs
- chronic alcoholism
- destruction or sequestration by spleen
- disease of leukemia or bone marrow
Reference range for RBC indices is?
MCV: 80-98fL if <80fL = microcytic; >98=Macrocytic
MCHC: 32%-37% if <32% = hypochromic
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