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remnants of RNA and other basophilic nuclear material remaining inside the red blood cell after the nucleus is lost from the cell; small purple granules in red blood cells stained with Wright’s stain
elongated, cigar-shaped red blood cell
an immature blood cell normally found only in the bone marrow
the appearance of an increased number of immature neutrophil forms in the peripheral blood
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List three conditions in which abnormal RBC morphology can be found?
- Iron deficiency anemia
- Folic Acid deficiency
- Vitamin B12 deficiency
- sickle cell disease
How can RBC indices be used to classify anemias?
List three conditions in which abnormal WBC morphology can be found?
characteristic of chronic leukemias?
Chronic: worsen slowly total number of abnormal WBC small. abnormal cells still function to some extent. Bone marrow not affected to large degree.
List cause of thrombocytosis ?
- elevated platelet do to:
- reaction to inflammatory condition
- secondary to other blood disorders
- removal of the spleen
characteristic of acute leukemia?
- worsen rapidly
- abnormal immature cells that cannot carry out normal immune function.
List cause of thrombocytopenia.
- decreased platelet count do to:
- radiation exposure
- some drugs
- chronic alcoholism
- destruction or sequestration by spleen
- disease of leukemia or bone marrow
Reference range for RBC indices is?
MCV: 80-98fL if <80fL = microcytic; >98=Macrocytic
MCHC: 32%-37% if <32% = hypochromic
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