Epinephrine(Adrenalin) Final Review

The flashcards below were created by user Lhernandez on FreezingBlue Flashcards.

  1. Epinephrine(Adrenalin) Class
  2. Epinephrine(Adrenalin) MOA
    • Direct acting alpha/beta agonist
    • Alpha: Vasoconstriction
    • Beta-1: Positive Inotropic, Chronotropic and Dromotropic effects
    • Beta-2: Bronchial smooth muscle relaxation and dilation of skeletal vasculature
  3. Epinephrine(Adrenalin) Indication
    • Cardiac Arrest(V-fib, Pulseless V-Tach, Asystole, PEA)
    • Symptomatic bradycardia as an alternative infusion to Dopamine
    • Severy hypotension secondary to bradycardia when Atropine and transcutaneous pacing are unsuccessful
    • Allergic reaction
    • Anaphylaxis
    • Asthma
  4. Epinephrine(Adrenalin) Contraindication
    • Hypothermia
    • Pulmonary edema
    • Myocardial ischemia
    • Hypovolemic shock

    • Relative Contraindication:
    • Underlying cardiovascular disease/angina
    • Hypotension
    • Pregnancy
    • Pts over 40yrs
    • Hyperthyroidism
  5. Epinephrine(Adrenalin) Adverse
    • Hypertension
    • Tachycardia
    • Arrhythmias
    • Pulmonary edema
    • Anxiety
    • Restlessness
    • Psychomotor agitation
    • Nausea
    • Headache
    • Angina
  6. Epinephrine(Adrenalin) Dosage
    • Adult: 
    • Mild allergic reaction and asthma: 0.3-0.5mg 1:1,000 SQ
    • Anaphylaxis: 0.05-0.1mg 1:10,000 IV/IO over 5mins
    • Cardiac arrest:
    • IV/IO: 1mg 1:10,000 every 3-5mins during resuscitation. Follow each dose with 20mL flush and elevate arm for 10-20sec after dose. Higher doses(up to 0.2mg/kg) may be administered for specific conditions(beta-blocker/Calcium channel-blocker OD)
    • ET: 2-2.5mg diluted in 10mL NS
    • Continuous Infusion: Add 1mg of 1:1,000) to 500mL of NS or D5W. Initial infusion rate of 1mcg/min titrated to effects(typical dose 2-10mcg/min)Profound hypotension: 2-10mcg/min titrated

    • Peds: 
    • Mild allergic reaction and asthma: 0.01mg/kg of 1:1,000 SQ Max 0.3mg
    • Cardiac arrest: 
    • IV/IO:  0.01mg/kg of 1:10,000 every 3-5mins during arrest
    • ET: 0.1mg/kg of 1:1,000
    • Continuous IV infusion: Begin with rapid infusion, then titrate to response. Typical initial infusion- 1mcg/min. Higher doses may be effective

Card Set:
Epinephrine(Adrenalin) Final Review
2015-04-01 23:43:32
Drug Profiles,Final Review
Show Answers: