Lidocaine Hydrochloride (Xylocaine) Final Review

Anti-arrhythmic

• Decrease automaticity by slowing rate of phase 4 depolarization
• Supresses ventricular ectopy
• Increases the fibrilation threshold

• Malignant PVCs
• V-Tach
• V-Fib
• Sometimes as premed for RSI

• Hypersensitivity
• 2nd/3rd degree hb
• Wide complex ventricular escape beats with bradycardia

• Slurres speech
• Seizure
• AMS
• Confusion
• Lightheaded
• Blurred vision
• Bradycardia

Adult: Inital 1-1.5 mg/kg IV/IO may repeat in 5-10min at 0.5-0.75 mg/kg to a max dose of 3 mg/kg

ET: 2-4 mg/kg

Stable V-Tach: 0.5-0.75 mg/kg and up to 1-1.5 mg/kg repeat 0.5-0.75 mg/kg to a max dose of 3 mg/kg

Maintence Infusion: 1-4 mg/min in NS or D5W