Mycology Part 2.txt

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  1. Basidobolus is associated with ___________________; it causes __________ infections in...
    dung of amphibians, reptiles, bats in tropics; deep cutaneous infection; dogs, horses, humans
  2. Basidiobolus is a type of ____________.
  3. Mucor and Rhizopus are types of _____________ that only infect....
    Zygomycosis; severely immunocompromised patients
  4. To diagnose Mucor and Rhizopus, you must...
    combine culture and histopathology (ubiquitous so culture does not mean infection)
  5. Candidiasis is ________; it is part of the _________ of... (3)
    yeast; normal flora; fecal, cutaneous, and mucous membranes
  6. Candidiasis cause mucosal infection of the.... (3)
    mouth, bladder, GI
  7. What stain can you use to see candidiasis?
    silver stain
  8. Candida peritonitis in dog is associated with...
    rupture of upper GI or biliary tract
  9. Aspergillus fumigatus is ____________ in the environment.
  10. _____________ is not required for formation of mycetomas; common in the __________ of horses with __________.
    Immunosupression; gutteral pouch; Aspergillus
  11. Fungal differential for canine nasal Aspergillus.
    Pseudallescheria boydii
  12. What stain can you use to visualize Pseudallescheria boydii?
    PAS stain
  13. What to fungi can cause mycotic abortion in cattle, likely associated with the quality of the hay/silage?
    Aspergillus fumigatus, Mucor spp.
  14. Mycotic keratitis occurs in __(2)__ after spores invade via ________; 3 causative fungi include...
    horses, dogs; corneal injury; Aspergillus, Fusarium, Alternaria
  15. Diagnosis of mycotic keratitis is by...
    cytology, culture
  16. Cryptococcus neoformans is __________ in the environment but enriched in pigeon dropping because of high ________.
    ubiquitous; creatinine
  17. Cryptococcus gatti is present on...
    eucalyptus, douglas fir trees
  18. Cryptococcosis grows as a __________ and causes disease when...
    yeast; there is high innoculum or immunosuppression
  19. Cryptococcus gatti affects horses in the __________; it also affects...
    pacific NW; cats, dogs, humans
  20. Cryptococcosis enters through penetration of ___________; it mounts an inflammatory response that is __________ in immunocompromised and __________ in the healthy.
    respiratory epithelium; minimal; granuloma forming
  21. Cryptococcosis has a tropism for __________ tissues, such as...
    cooler; respiratory, skin, CNS, eye
  22. Cryptococcosis is diagnosed by... (4)
    cytology, histopath, culture, Ag detection in serum
  23. How do you manage an infection with Cryptococcosis? (2)
    manage underlying immunosuppression, itraconazole/fluconazole
  24. What are the 3 systemic mycoses?
    Blastomyces dermatitidis, Histoplasma capsulatum, Coccidoides immitis
  25. ____________ is not a requirement for infection with systemic mycoses.
  26. Blastomycosis is located in what regions?
    eastern and midwestern US
  27. Blastomycosis causes disease in...
    dogs, humans
  28. Blastomycosis is __________, meaning...
    thermally dimorphic; mold at 25°C and yeast at body temp
  29. Which is the infectious form of Blastomycosis?
    mold form
  30. Blastomycosis enters the body through...
    inhalation of mold --> transformation to yeast in vivo
  31. Initial infection with Blastomycosis is __________; then, it disseminate to...
    pulmonary; bone, CNS, skin
  32. Blastomycosis causes ___________ inflammation.
  33. Infection with Blastomyces dermatitidis is enhanced by ______________.
    corticosteroid administration
  34. A useful method of diagnosing Blastomyces dermatitidis is detection of __________ in __________.
    galactomannan Ag; urine
  35. What is the treatment for infection with Blastomyces?
    systemic antifungals- amphotericin B, itraconazole, fluconazole
  36. Blastomyces is not really __________, but it can be.
  37. What is the regional location of Histoplasma capsulatum?
    midwest and south central US (especially Ohio)
  38. Histoplasma capsulatum is found in __________; it causes disease in...
    bird/bat droppings; cats, dogs, humans
  39. Histoplasma capsulatum is __________, and it is not _________.
    thermally dimorphic; zoonotic
  40. Histoplasma capsulatumm enters the body through _______________, causing _________ lesions, which eventually disseminate to...
    inhalation of mold; pulmonary; small intestine, liver, lymph nodes, spleen, eye
  41. Histoplasma capsulatum may present as a ______________.
    wasting syndrome
  42. Diagnosis of Histoplsmosis is by... (5)
    cytology, histo, culture, serology, urine antigen test
  43. How do you treat infection with Histoplasmosis? (2)
    systemic antifungals, glucocorticoids in dogs
  44. Coccidioides immitus is located in what region?
    lower sonoran life zones in alkaline soil of southwestern US
  45. Coccidioides immitus causes _________ in...
    valley fever; dogs, cats, horse
  46. Coccidioides immitus expresses _________, it is not ________-dependent.
    tissue dimorphism; temperature
  47. Coccidioides immitus enters the body through _________, causing _________; it disseminates through _________.
    inhalation; lung infection; lymphatics
  48. Diagnosis of Coccidiomycosis is by... (4)
    cytology, histo, culture, serology
  49. How do you treat Coccidiomycosis? (3)
    azoles, amphotericin B, cease glucocorticoid drugs
  50. Why do you not bandage draining tracts associated with Coccidiomyccosis?
    infectious mycelial phase ca grow in bandage material
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Mycology Part 2.txt
2015-04-14 20:46:05
vetmed mycology

vetmed, mycology part 2
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