Mycology Part 2.txt
Card Set Information
Mycology Part 2.txt
vetmed, mycology part 2
Basidobolus is associated with ___________________; it causes __________ infections in...
dung of amphibians, reptiles, bats in tropics; deep cutaneous infection; dogs, horses, humans
Basidiobolus is a type of ____________.
Mucor and Rhizopus are types of _____________ that only infect....
Zygomycosis; severely immunocompromised patients
To diagnose Mucor and Rhizopus, you must...
combine culture and histopathology (ubiquitous so culture does not mean infection)
Candidiasis is ________; it is part of the _________ of... (3)
yeast; normal flora; fecal, cutaneous, and mucous membranes
Candidiasis cause mucosal infection of the.... (3)
mouth, bladder, GI
What stain can you use to see candidiasis?
Candida peritonitis in dog is associated with...
rupture of upper GI or biliary tract
Aspergillus fumigatus is ____________ in the environment.
_____________ is not required for formation of mycetomas; common in the __________ of horses with __________.
Immunosupression; gutteral pouch; Aspergillus
Fungal differential for canine nasal Aspergillus.
What stain can you use to visualize Pseudallescheria boydii?
What to fungi can cause mycotic abortion in cattle, likely associated with the quality of the hay/silage?
Aspergillus fumigatus, Mucor spp.
Mycotic keratitis occurs in __(2)__ after spores invade via ________; 3 causative fungi include...
horses, dogs; corneal injury; Aspergillus, Fusarium, Alternaria
Diagnosis of mycotic keratitis is by...
Cryptococcus neoformans is __________ in the environment but enriched in pigeon dropping because of high ________.
Cryptococcus gatti is present on...
eucalyptus, douglas fir trees
Cryptococcosis grows as a __________ and causes disease when...
yeast; there is high innoculum or immunosuppression
Cryptococcus gatti affects horses in the __________; it also affects...
pacific NW; cats, dogs, humans
Cryptococcosis enters through penetration of ___________; it mounts an inflammatory response that is __________ in immunocompromised and __________ in the healthy.
respiratory epithelium; minimal; granuloma forming
Cryptococcosis has a tropism for __________ tissues, such as...
cooler; respiratory, skin, CNS, eye
Cryptococcosis is diagnosed by... (4)
cytology, histopath, culture, Ag detection in serum
How do you manage an infection with Cryptococcosis? (2)
manage underlying immunosuppression, itraconazole/fluconazole
What are the 3 systemic mycoses?
Blastomyces dermatitidis, Histoplasma capsulatum, Coccidoides immitis
____________ is not a requirement for infection with systemic mycoses.
Blastomycosis is located in what regions?
eastern and midwestern US
Blastomycosis causes disease in...
Blastomycosis is __________, meaning...
thermally dimorphic; mold at 25°C and yeast at body temp
Which is the infectious form of Blastomycosis?
Blastomycosis enters the body through...
inhalation of mold --> transformation to yeast in vivo
Initial infection with Blastomycosis is __________; then, it disseminate to...
pulmonary; bone, CNS, skin
Blastomycosis causes ___________ inflammation.
Infection with Blastomyces dermatitidis is enhanced by ______________.
A useful method of diagnosing Blastomyces dermatitidis is detection of __________ in __________.
galactomannan Ag; urine
What is the treatment for infection with Blastomyces?
systemic antifungals- amphotericin B, itraconazole, fluconazole
Blastomyces is not really __________, but it can be.
What is the regional location of Histoplasma capsulatum?
midwest and south central US (especially Ohio)
Histoplasma capsulatum is found in __________; it causes disease in...
bird/bat droppings; cats, dogs, humans
Histoplasma capsulatum is __________, and it is not _________.
thermally dimorphic; zoonotic
Histoplasma capsulatumm enters the body through _______________, causing _________ lesions, which eventually disseminate to...
inhalation of mold; pulmonary; small intestine, liver, lymph nodes, spleen, eye
Histoplasma capsulatum may present as a ______________.
Diagnosis of Histoplsmosis is by... (5)
cytology, histo, culture, serology, urine antigen test
How do you treat infection with Histoplasmosis? (2)
systemic antifungals, glucocorticoids in dogs
Coccidioides immitus is located in what region?
lower sonoran life zones in alkaline soil of southwestern US
Coccidioides immitus causes _________ in...
valley fever; dogs, cats, horse
Coccidioides immitus expresses _________, it is not ________-dependent.
tissue dimorphism; temperature
Coccidioides immitus enters the body through _________, causing _________; it disseminates through _________.
inhalation; lung infection; lymphatics
Diagnosis of Coccidiomycosis is by... (4)
cytology, histo, culture, serology
How do you treat Coccidiomycosis? (3)
azoles, amphotericin B, cease glucocorticoid drugs
Why do you not bandage draining tracts associated with Coccidiomyccosis?
infectious mycelial phase ca grow in bandage material