-Cyanosis: Bluish discoloration of skin and mucous Membranes --redueced Hgb, excessie concentration of deoxyhemoglobin in blood
-Excoriation: scratch ofr abrasion of skin: from inentse pruritus (unpleaseant cutaneous sesnation) could mean lymhoma, or increased biliruin
-Leg Ulcer: sickle cell disease
-Spider nevus: elevated estrogen levels as in pregnancy or liver disease
-Purpura, Petechia (pinpoint), hematomas (clotted localized blood): decreased platelets or clotting favtors resulting in hemmorrhage into the skin
-Chrloroma; tumor arising for myeloid tissue and containing a pale green pigment
-Plasmacytoma: tumor arising from abnormal plasma cells (means multiple myeloma that has infiltrated tissue)
-Jaundiced sclera: accumulationof bile pigment resulting from rapid or excessive hemolysis or liver disease or infliltration
-Conjunctival pallor: paleness/decrease coloration in the conjunctive:--low Hemoglobin level (anemia)
Blurred vision, diplopia,: --enemia, polycythemia
-Epistaxis: spontaneous bleeding from nares: may occur with low platelet counts, especially if bending down for a long time, performing valsava manuveer.
-Bone pain: Multiple myeloma
-Artharlgia: Joint pain; sickle cell.
: Lymph nodes enlarged: means infection, foreign infliltrations, systemic diseases (leukemia, lmphoma,metastatic cancer)
: palpable liver: leukemia, cirrhosis, fibrosiss secondary to iron overload from sickle cell disease or thalassemia
: palpable spleen: anemia, thrombocytop;enia, leukemia, lymphomas, malaria, cirrhosis, trauma, portal HTN.
-Parastehsias: cobalamin deficiency
-Weakness: anaemia/low hgb level
- Headache (severe): thrombocytopenia Inter crani
- al hemmorahage.