Hem Lec 22

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  1. Patients with some variety of MDS are at increased risk of developing?
  2. Which of the following agents has not been supported by scientific research as being associated with the development of secondary MDS?
    • Organic solvents
    • Insecticides
  3. An increased incidence of MDSs is seen in?
    males older than 55 years of age
  4. The most frequently involved chromosomes in adults with MDS are?
    chromosome 5, 7, and 8
  5. The most frequent chromosomal abnormalities in children with MDS include all of the following except?
    • trisomy 8
    • monosomy 7
    • deletion of long arm of chromosome 20
  6. The incidence of chromosomal abnormality in adults with MDS is?
    40% to 90%
  7. The karyotype associated with a high probability of transforming to AML is?
    • monosomy 5
    • monosomy 7
  8. Patients with MDSs commonly suffer from _____ initially.?
  9. In young patients, the therapy of choice for MDSs involves?
    allogeneic bone marrow transplantation
  10. anemia, no blasts
    Refractory anemia with ring sideroblasts (RARS)
  11. anemia, less than 1% blasts?
    Refractory anemia (RA)
  12. cytopenia(s), less than 5% blasts, no Auer rods
    Refractory anemia with excess blasts, type 1 (RAEB-1)
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Hem Lec 22
2015-04-29 22:10:20
Hem Lec 22
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Hem Lec 22
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