Home > Flashcards > Print Preview
The flashcards below were created by user
on FreezingBlue Flashcards. What would you like to do?
Describe penicillin, the class, where is it metabolized? How should it be given? Whats the indication? Action? Side effects? Drug-drug interaction?
- Ampicillin, piperacillin, oxacillin
- Class: antiinfective
- Metabolized: in the duodenum and jejunum
- Give: PO, deep IM, IV; PO on an empty stomach (1 hr before, 2hrs after) so the gut has a chance to absorb
- Indications: soft tissue infections
- Action: destroys cell wall, a broad spectrum of bacteria
- SE: Gut, NVD, Lethargy, anxiety, depression, seizures
- Drug-drug: don't give with aminoglycosides
Describe aminoglycosides which was the first developed? how is it excreted? action? Side effects?
- Streptomycin was first; gentamicin, kanamycin, neomycin, tebramycin
- Excreted: by kidneys
- Action: disrupts protein synthesis
- Side effects: ototoxicity, nephrotoxicity, anaphylaxis
Describe cephalosporins action, side efects, where is it excreted? when should you administer?
- First gen: cefazolin, cefalexin
- Second gen: cefoxitin
- third gen: cefotaxine
- fourth gen: cefepime
- similar reaction to penicillin; not absorbed in the GI tract; culture before wound prior
- Action: inhibits protein and cell wall synthesis
- Side effects: diarrhea, rash
- Monitor: for superinfection
- excreted: by kidneys or in bile
- Administer: 1 hour before other antibiotics
describe tetracyclines. where is it absorbed? excreted? action? indication? how should you give it? side effects?
- broad spectrum antibiotic; sumycin, minocin;
- absorbed: by the duodenum
- excreted: by the kidneys
- Action: inhibits protein synthesis in the cell
- indication: tx for acne and gonorrhea
- Given: i hr before or 2 hrs after meals; milk decreases absorption; dont give within 1 hr of bedtime
- Side effects: N/V, heartburn, steatorrhea, anaphylaxis, superinfection, abdominal distress, hepatotoxicity, renal toxicity, discoloration of the tooth enamel,
describe fluoroquinolones indication, excreted? action? side effects?
- ciprofloxacin, levofloxacin, moxifloxacin
- excreted: in urine, give with 8 oz water
- action: interrupt DNA syntesis
- side effects:
describe sulfonamides, side effects? action?
- side effects: N/V/D, dizziness, abdominal pain, tinnitus
- sulfadiazines, sulfasalazine, sulfisoxazole