how many strands of RNA are present in the AIDS virus structure?
true or false
AIDS virus contains a reverse transcriptase enzyme.
what are the two components fo the outer envelope of the AIDS virus?
what are the two glycoproteins found in the aids virus outer envelope?
what is the primary composition of the core of the AIDS virus?
what two structures in the core of the AIDS virus and what is their composition?
virus binds to ___ receptors on target cells.
what are the four cells that the AIDS virus binds to?
5% of B lympsh
what percent of B lymphs does the AIDS virus bind to?
this convers RNA into proviral DNA?
this is the causative agent of AIDS in the U.S. and europe
this is associated with immunodeficiency and AIDS in west africa
period between infection and disease may be longer and milder in which form of AIDS?
Ab to HIV-1 appear at about __ weeks after infection.
this type of HIV antibody is not routinely tested alone.
this is the most widely used screening test for AIDS.
true or false
Reactive AIDS results must be retested and confirmed.
if __ out of __ EIA results for AIDS are reactive, report out "repeatedly reactive."
2 out of 3
This could cause a false negative on EIA for AIDS.
not enough antibody to be detected (incubation)
this could cause a false positive on EIA for AIDS.
autoimmune disease and heat treated specimens
what is the confirmation test for AIDS?
western blot test
in this test, HIV proteins are separated by electrophoresiss, then transferred to nitrocellulose sheets cut into strips. which are incubaed then substrate is added for color which deveops where Ag-Ab reactions occur.
on the western blot test, where does color develop?
where Ag-Ab reactions occur
on the western blot test, the presence of what two proteins, in conjunction with a postive EIA, are considered positive?
this retrovirus is linked to adult T-cell leukemia and transmitted by transfer of infected cells.
this retrovirus is linked to hairy cell leukemia?
what are three methods used as initial screening methods for other human retroviruses?
what is the confirmatory method for other human retroviruses?
immunoblots (i.e. Western blot)
what is the name of the virus that is a memeber of the herpes family which has caused a worldwide endemic?
what are the five means by which cytomegalovirus may be transmitted?
what three fluids may the cytomegalovirus be present in?
what are the two forms of infection in cytomegalovirus?
by adulthood, most individuals have experience asymptomatic contact of this virus.
in cytomegalovirus, occcasionally self-limited, heterophile negative symptoms occur that resemble what illness?
what are the four signs and symptoms of cytomegalovirus?
active CMV infection may be life-threatening for who?
this is one of the most important cause of congenital viral infections in the U.S.
Majority of CMV infected newborns are asymptomatic but ___ manifest damage caused by CMV.
in cytomegalovirus, infected infants can become severely ill and death may occur in __________ infants.
in cytomegalovirsu reactivation of infection in seropositive patients may have increase in ____ antibodies.
what are the three testing methods used to detect cytomegalovirus antibodies?
what is the only testing method to detect cytomegalovirus antigens?
what are the specimen requirements for cytomegalovirus?
2ml serum or anticoagulated blood (lavender top)
what are the two most common manifestations of HSV?
HSV belongs to the herpes family along with what other three viruses?
epstein barr virus
this virus is generally found in and around oral cavity and skin lesions above waist.
herpes simplex virus type 1
transmission of this herpes virus is usually non-venereal.
this virus is isolated primarily from genital tract and skin lesion below the waist.
herpes simplex virus type 2
transmission of this type of herpes is venereal.
what is the predominant age group for HSV-1
what is the predominant age group for HSV 2?
what are the three testing methods for HSV antigens?
what are the three testing methods for HSV antibodies.
a ____ fold increase or greater in titer indicates primary infection
this virus is also know as german measles.
this is a highly contagious, endemic virus that is transmitted by respiratory secretion.
before widespread immunization of rubella, infection occured mostly in ____________.
what is the incubation period for rubella?
how long are infected persons contagious for? before rash?
infecition by this virus usually lasts for 3-5 days and generally requires little treatment.
pregnant women infected with rubella in what trimester can have devestating effects on fetus?
in-utero infection of rubella can result in fetal death or __________ syndrome.
what are three signs and syndromes of rubella syndrome?
what are the three testing methods for rubella?
what is the testing method used for rapid and convenient testing of rubella?
what is the reference method used in rubella?
what are the specimen requirements for quantitative testing of rubella?
two specimens required
first within 3 days of rash onset
second 7-21 days after onset or rast or 30 days after exposure
when collecting two specimens for rubella, they should be tested ______________.
how long are EIA rubella specimens good for if refigerated at 2-8oC?
if delays for more than 72 hours are expected in EIA rubella testing they should be stored at what temperature?
TORCH is an acronym for what four infectious diseases?
true or flase
torch disease cannot cause illness in pregnant women or cannnot cause birth defects in the newborn
what is the testing method for TORCH?
TORCH testing screens for the presence of __________ to any of the infections.
the presence of ____ or ____ in TORCH indicates a recent or current infection.