SGU SVM Immunology

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SGU SVM Immunology
2010-08-17 20:36:39
SGU SVM Immunology

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  1. Immunity
    Body defenses that protect againts disease
  2. Types of Defense
    • 1) Physical Barriers
    • 2) Innate Immunity
    • 3) Acquired Immunity
    • 4) Passive Immunity
  3. Innate Immunity
    Chemicals and Cells

    No Memory

    Responds Immediately
  4. Acquired Immunity
    Can recognize foreign invaders with specificity, destroy them, and retain the memory of the specific encounter.
  5. Which two forms of Acquired Immunity communicate with each other?
    Humoral Immunity and Cell-Mediated Immunity
  6. Humoral Immunity
    Targets invaders outside of cells via B-lymphocytes
  7. Cell Mediated Immunity
    Targets cells of the body that are infected with Intracellular pathogens via T-lymphocytes
  8. Dysregulations of the Immune System
    • 1) Hypersensitivities
    • 2) Autoimmunity
    • 3) Immunodeficiencies
    • 4) Neoplasia of Immune System
  9. Phagocytic Cells of the Innate Immune System

    Polymorphonuclear Cells
  10. Natural Killer Cells
    Don't recognize the antigen, they recognize infected cells by other mechanisms
  11. Soluble Defense Factors
    • 1) Enzymes
    • 2) Defensins
    • 3) Interferons
  12. Enzymes
    Cause damage to membranes
  13. Defensins
    Anti-bacterial peptides
  14. Interferons
    Cytokines that can interfere with viral replication
  15. Cytokines
    Proteins that mediate cellular interactions and regulate cell growth and secretion.
  16. Complement Proteins
    Group of serum and cell surface proteins that can be activated by both innate and acquired immune mechanisms and result in a variety of biological events.

    • 1) Cell Lysis
    • 2) Chemotaxis
    • 3) Opsonins