DL - Final 2
Card Set Information
DL - Final 2
DL - Final
The first time that you fill an antidepressant, you should ask the patient what?
“Are you thinking about harming or killing yourself?”
If the risk is significant, the patient should be referred immediately to an appropriate health care professional.
You can continue to ask in future situations
What are the SSRIs?
How should you instruct patients about antidepressant use?
4 weeks or longer for effect
Continue taking even if not feeling better right away
Watch for worsening or changes in feelings
Do not suddenly stop – talk to doc first
Drowsiness or dizziness
Black Box Warning and Med Guide
How do SSRIs compare to TCAs?
When given with what other drugs can SSRIs cause Seratonin Syndrome?
St. John's Wort
Taking SSRIs alongside many similar drugs can make new bad listeners
What are the general Disadvantages of SSRIs?
(Last two are transient)
What are the dosages forms available for Zoloft?
25, 50, 100 mg
20 mg/mL oral concentrate
How many active metabolites does Zoloft have?
One less active metabolite
What DDIs does Zoloft have?
2D6 (less than Fluoxetine or Paroxetine)
What is Zoloft approved to treat?
What special information should you tell a patient about Zoloft?
Take w/ food to decrease GI upset
: dilute right before admin in >4 oz beverage
Beverage must be
: Ginger ale, water, lemon lime soda, lemonade, orange juice
What should you know about the pharmacokinetics of Zoloft?
Elderly clear it 40% less
Dose reduce in liver failure due lengthened t1/2
Unchanged kinetics in moderate – severe renal impairment
What are the dosage forms available for Celexa?
10, 20, 40 mg tabs
Oral solution 10mg/5 mL
How/When should Celexa be given?
Morning or evening w/ or without food
What are the dosage forms available for Lexapro
5,10,20 mg, 5mg/5ml solution
How/When should Lexapro be given?
with or without food
morning or night
Nausea is problematic = take after a meal
Take with a full glass of water
What special information should you counsel a patient on regarding Lexapro?
Tablets are scored and may be cut in half if needed